SCHEMBL150540

SCHEMBL150540

CC(=O)O[Si](C)(OC(C)=O)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.43
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
ALDH1A1 P00352 4/20 0.41
ESR1 P03372 2/20 0.39
ESR2 Q92731 1/20 0.39
HSD17B10 Q99714 3/20 0.38
HPGD P15428 3/20 0.38
TSHR P16473 2/20 0.38
NAPRT Q6XQN6 2/20 0.38
KDM4E B2RXH2 2/20 0.38
ELANE P08246 1/20 0.38
ITGB3 P05106 1/20 0.38
ITGA2B P08514 1/20 0.38
HMGB1 P09429 1/20 0.38
GGT1 P19440 1/20 0.38
PTGS1 P23219 1/20 0.38
PTGS2 P35354 1/20 0.38
BLM P54132 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19858489 0.90 TSHR (0.41) MAPTCES2CES1ALDH1A1ESR1
SCHEMBL705277 0.89 HPGD (0.38) MAPTALDH1A1HPGDTSHRPOLB
SCHEMBL11186822 0.88 TDP1 (0.40) MAPTCES2CES1ALDH1A1ESR1
SCHEMBL475923 0.83 MAPT (0.43) MAPTCES2CES1ALDH1A1ESR1
SCHEMBL475969 0.83 MAPT (0.43) MAPTCES2CES1ALDH1A1ESR1
SCHEMBL9411498 0.82 ELANE (0.45) MAPTCES2CES1ALDH1A1ESR1
SCHEMBL27743553 0.81 ESR1 (0.42) MAPTALDH1A1ESR1ESR2HSD17B10
SCHEMBL132756 0.80 CES2 (0.43) MAPTCES2CES1ALDH1A1ESR1
SCHEMBL132933 0.80 CES2 (0.43) MAPTCES2CES1ALDH1A1ESR1
SCHEMBL476126 0.80 CES2 (0.43) MAPTCES2CES1ALDH1A1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 642 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025040760-A1 COATING COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2025-02-27 WO claimed
CN-116731522-A High-temperature-resistant rubber sealing ring material for inspection well and preparation method thereof 河北益泽电讯科技有限公司 2023-09-12 CN claimed
EP-2567986-B1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF PETROCHINA CO LTD (CN) 2022-04-13 EP claimed
CN-105544199-B The comfortable finishing technique of high-count cashmere 湖州珍贝羊绒制品有限公司 2017-08-04 CN claimed
CN-105544199-A High count cashmere yarn comfort finishing process HUZHOU ZHENBEI CASHMERE PRODUCTS CO LTD 2016-05-04 CN claimed
US-8716417-B2 Olefin polymerization catalyst and preparation method and use thereof PETROCHINA COMPANY LIMITED (CN) 2014-05-06 US claimed
US-6969753-B2 Spin-on-glass anti-reflective coatings for photolithography HONEYWELL INTERNATIONAL INC. (US) 2005-11-29 US claimed
EP-0799851-A2 Preparation of polyorganosilloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-10-08 EP claimed
US-5629401-A Preparation of polyorganosiloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-05-13 US claimed
US-4039666-A ANTICONVULSANT PHENYLSILANES DOW CORNING CORPORATION (US) 1977-08-02 US claimed
US-12624168-B2 Methods for making polyfunctional organosiloxanes and compositions containing same DOW SILICONES CORPORATION (US) 2026-05-12 US disclosed
US-20260118764-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM AND SILICON-CONTAINING RESIST UNDERLAYER FILM NISSAN CHEMICAL CORPORATION (JP) 2026-04-30 US disclosed
EP-4724410-A1 HYDROPHOBIZED RECYCLED CONCRETE AGGREGATES, METHODS FOR THEIR MANUFACTURE, AND USE OF THE HYDROPHOBIZED RECYCLED CONCRETE AGGREGATES IN CEMENTITIOUS COMPOSITIONS Sika Technology AG (CH) 2026-04-15 EP disclosed
EP-4715465-A1 MULTILAYER BODY, METHOD FOR PRODUCING MULTILAYER BODY, AND PHOTOSENSITIVE SURFACE MODIFIER Nissan Chemical Corporation (JP) 2026-03-25 EP disclosed
US-12585188-B2 Composition for forming resist underlying film NISSAN CHEMICAL CORPORATION (JP) 2026-03-24 US disclosed
US-4678468-A HEPARIN IN INTERPENETRATING POLYMER NETWORK BIO-MEDICAL CO., LTD. (JP) 1987-07-07 US disclosed
US-4602065-A Silicon-containing step ladder polymer and a process for producing the same CHISSO CORPORATION (JP) 1986-07-22 US disclosed
EP-0182948-A1 Silicon-containing step ladder polymer and a process for producing the same Chisso Corporation (JP) 1986-06-04 EP disclosed
US-4585834-A FROM A POLYVINYL SILANE PREPOLYMER CHISSO CORPORATION (JP) 1986-04-29 US disclosed
US-4066680-A PROCESS FOR MAKING ALPHA,OMEGA-SILOXANEDIOLS SWS SILICONES CORPORATION (US) 1978-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260118764-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM AND SILICON-CONTAINING RESIST UNDERLAYER FILM SRSF1, MACF1, SRPK1 MAPT 965/4885CES2 2753/4885CES1 2191/4885
US-12585188-B2 Composition for forming resist underlying film SRR, SMC1A, ASH2L MAPT 4790/4885CES2 995/4885CES1 762/4885
US-12624168-B2 Methods for making polyfunctional organosiloxanes and compositions containing same HAO2, H1-2, HRH2 MAPT 4732/4885CES2 597/4885CES1 1818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.