Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MLYCD | O95822 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 3/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9598862 | 0.88 | TSHR (0.55) | TSHRMLYCDCA2CA1CA9 | |
| SCHEMBL9550971 | 0.83 | TSHR (0.50) | TSHRMLYCDCA2CA1CA9 | |
| SCHEMBL17943301 | 0.81 | TSHR (0.48) | TSHRMLYCDCA2CA1CA9 | |
| SCHEMBL12299037 | 0.81 | TSHR (0.55) | TSHRMLYCDCA2CA1CA9 | |
| SCHEMBL30144865 | 0.81 | TSHR (0.48) | TSHRMLYCDCA2CA1CA9 | |
| SCHEMBL5753370 | 0.81 | TSHR (0.55) | TSHRMLYCDCA2CA1CA9 | |
| SCHEMBL11217955 | 0.80 | TSHR (0.42) | TSHRMLYCDCA2CA1CA9 | |
| SCHEMBL2776477 | 0.80 | MLYCD (0.50) | TSHRMLYCDCA2CA1CA9 | |
| SCHEMBL17943229 | 0.79 | TSHR (0.48) | TSHRCA2CA1CA9CA5A | |
| SCHEMBL11358160 | 0.78 | TSHR (0.50) | TSHRMLYCDCA2CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118119583-A | Method for producing fluorine-containing aromatic compound | 大金工业株式会社 | 2024-05-31 | — | — | CN | disclosed |
| WO-2024017977-A1 | IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2024-01-25 | — | — | WO | disclosed |
| US-20220105462-A1 | m-PHENYLENEDIAMINE COMPOUND, POLYMER AND METHOD FOR PRODUCING THE SAME, AND GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, AND GAS SEPARATION APPARATUS USING THE POLYMER | FUJIFILM CORPORATION (JP) | 2022-04-07 | — | — | US | disclosed |
| US-20210070713-A1 | PESTICIDAL COMPOUNDS | BASF SE (DE) | 2021-03-11 | — | — | US | disclosed |
| WO-2021014821-A1 | M-PHENYLENEDIAMINE COMPOUND, POLYMER AND METHOD FOR PRODUCING SAME, GAS SEPARATION MEMBRANE USING THIS POLYMER, GAS SEPARATION MODULE AND GAS SEPARATION APPARATUS | 富士フイルム株式会社 | 2021-01-28 | — | — | WO | disclosed |
| WO-2020243423-A1 | TEAD INHIBITORS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2020-12-03 | — | — | WO | disclosed |
| US-10720584-B2 | Charge-transporting varnish, and organic electroluminescent element | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2020-07-21 | — | — | US | disclosed |
| EP-3404017-B1 | FLUORINE ATOM-CONTAINING COMPOUND AND USE THEREOF | NISSAN CHEMICAL IND LTD (JP) | 2020-05-13 | — | — | EP | disclosed |
| US-10336686-B2 | Fluorine atom-containing compound and use thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2019-07-02 | — | — | US | disclosed |
| US-10301484-B2 | Varnish for formation of charge-transporting thin film | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2019-05-28 | — | — | US | disclosed |
| US-20030027826-A1 | (R)-Chiral halogenated substituted heteroaryl benzyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | SIKORSKI JAMES A (US) | 2003-02-06 | — | — | US | disclosed |
| US-20020177708-A1 | (R)-chiral halogenated substituted N-benzyl-N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | SIKORSKI JAMES A (US) | 2002-11-28 | — | — | US | disclosed |
| EP-1115695-A1 | (R)-CHIRAL HALOGENATED 1-SUBSTITUTEDAMINO-(N+1)-ALKANOLS USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | Monsanto Company (US) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000018724-A1 | (R)-CHIRAL HALOGENATED 1-SUBSTITUTEDAMINO-(n+1)-ALKANOLS USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | MONSANTO COMPANY (US) | 2000-04-06 | — | — | WO | disclosed |
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| US-5650533-A | Intermediates to herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-22 | — | — | US | disclosed |
| EP-0418175-B1 | Isoxazoles herbicides | RHONE POULENC AGRICULTURE (GB) | 1996-07-17 | — | — | EP | disclosed |
| EP-0418175-A2 | Isoxazoles herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1991-03-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10336686-B2 | Fluorine atom-containing compound and use thereof | ARF1, ARF5, ARFGAP1 | TSHR 668/4885MLYCD 4283/4885CA2 2792/4885 |
| US-20220105462-A1 | m-PHENYLENEDIAMINE COMPOUND, POLYMER AND METHOD FOR PRODUCING THE SAME, AND GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, AND GAS SEPARATION APPARATUS USING THE POLYMER | CPNE4, SCO2, PRMT9 | TSHR 2040/4885MLYCD 63/4885CA2 912/4885 |
| US-20030027826-A1 | (R)-Chiral halogenated substituted heteroaryl benzyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | CETP, DBI, PLTP | TSHR 2313/4885MLYCD 3471/4885CA2 3960/4885 |
| US-20020177708-A1 | (R)-chiral halogenated substituted N-benzyl-N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | CETP, DBI, MTTP | TSHR 2273/4885MLYCD 3885/4885CA2 4534/4885 |
| US-20210070713-A1 | PESTICIDAL COMPOUNDS | CAT, NIT2, PNMT | TSHR 2952/4885MLYCD 1180/4885CA2 868/4885 |
| US-10720584-B2 | Charge-transporting varnish, and organic electroluminescent element | SLCO4C1, SLCO2A1, SLCO1A2 | TSHR 1557/4885MLYCD 3990/4885CA2 370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.