Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | IDO1 | P14902 | 4/20 | 0.58 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3244320 | 0.91 | CYP2C19 (0.63) | CYP2C19CYP1A2CYP2C9IDO1LOXL2 | |
| SCHEMBL7166059 | 0.84 | CYP2C19 (0.56) | CYP2C19CYP1A2CYP2C9IDO1LOXL2 | |
| SCHEMBL1035377 | 0.83 | CYP2C19 (0.81) | CYP2C19CYP1A2CYP2C9IDO1LOXL2 | |
| SCHEMBL11277119 | 0.81 | CYP2C19 (0.53) | CYP2C19CYP1A2CYP2C9IDO1LOXL2 | |
| SCHEMBL7244787 | 0.81 | CYP2C19 (0.79) | CYP2C19CYP1A2CYP2C9IDO1LOXL2 | |
| SCHEMBL8014656 | 0.79 | CYP2C19 (0.59) | CYP2C19CYP1A2CYP2C9IDO1LOXL2 | |
| SCHEMBL513720 | 0.79 | CYP2C19 (0.59) | CYP2C19CYP1A2CYP2C9IDO1LOXL2 | |
| SCHEMBL513721 | 0.79 | CYP2C19 (0.59) | CYP2C19CYP1A2CYP2C9IDO1LOXL2 | |
| SCHEMBL28866767 | 0.79 | IDO1 (0.62) | CYP2C19CYP1A2CYP2C9IDO1LOXL2 | |
| SCHEMBL7489100 | 0.78 | CYP2C19 (0.58) | CYP2C19CYP1A2CYP2C9IDO1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622507-B2 | Substituted organosulfur compounds and methods of using thereof | ACEA BIOSCIENCES INC. (US) | 2009-11-24 | — | — | US | claimed |
| EP-1742635-A2 | SUBSTITUTED ORGANOSULFUR COMPOUNDS AND METHODS OF USING THEREOF | Acea Biosciences, Inc. (US) | 2007-01-17 | — | — | EP | claimed |
| WO-2005112933-A2 | SUBSTITUTED ORGANOSULFUR COMPOUNDS AND METHODS OF USING THEREOF | ACEA BIOSCIENCES INC. (US) | 2005-12-01 | — | — | WO | claimed |
| US-20050261321-A1 | Substituted organosulfur compounds and methods of using thereof | ACEA Therapeutics, Inc. | 2005-11-24 | — | — | US | claimed |
| EP-1742635-B1 | SUBSTITUTED ORGANOSULFUR COMPOUNDS AND METHODS OF USING THEREOF | ACEA BIOSCIENCES INC (US) | 2018-03-07 | — | — | EP | disclosed |
| US-8334316-B2 | Substituted organosulfur compounds and methods of using thereof | ACEA BIOSCIENCES, INC. (US) | 2012-12-18 | — | — | US | disclosed |
| US-7622507-B2 | Substituted organosulfur compounds and methods of using thereof | ACEA BIOSCIENCES INC. (US) | 2009-11-24 | — | — | US | disclosed |
| US-20090192146-A1 | SUBSTITUTED ORGANOSULFUR COMPOUNDS AND METHODS OF USING THEREOF | ACEA BIOSCIENCES, INC. (US) | 2009-07-30 | — | — | US | disclosed |
| EP-1742635-A2 | SUBSTITUTED ORGANOSULFUR COMPOUNDS AND METHODS OF USING THEREOF | Acea Biosciences, Inc. (US) | 2007-01-17 | — | — | EP | disclosed |
| WO-2005112933-A2 | SUBSTITUTED ORGANOSULFUR COMPOUNDS AND METHODS OF USING THEREOF | ACEA BIOSCIENCES INC. (US) | 2005-12-01 | — | — | WO | disclosed |
| US-20050261321-A1 | Substituted organosulfur compounds and methods of using thereof | ACEA Therapeutics, Inc. | 2005-11-24 | — | — | US | disclosed |
| US-6555712-B2 | Reacting an organic halide and elemental sulfur (alpha -rhombic) using catalytic copper (II) halide and tin (II) halide in a mixture of organic solvents at 30-70 degrees C | INDIAN INSTITUTE OF TECHNOLOGY (IN) | 2003-04-29 | — | — | US | disclosed |
| US-20020198410-A1 | Process for the preparation of diorganotrisulfide | INDIAN INSTITUTE OF TECHNOLOGY | 2002-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192146-A1 | SUBSTITUTED ORGANOSULFUR COMPOUNDS AND METHODS OF USING THEREOF | TST, CTH, CBS | CYP2C19 4138/4885CYP1A2 3924/4885CYP2C9 3824/4885 |
| US-20020198410-A1 | Process for the preparation of diorganotrisulfide | TYR, DOHH, DECR1 | CYP2C19 1710/4885CYP1A2 876/4885CYP2C9 1803/4885 |
| US-20050261321-A1 | Substituted organosulfur compounds and methods of using thereof | TST, CTH, CBS | CYP2C19 4138/4885CYP1A2 3924/4885CYP2C9 3824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.