Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEH1 | O60930 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 6/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | APAF1 | O14727 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4019735 | 0.75 | HPGD (0.34) | HPGD | |
| SCHEMBL10953407 | 0.74 | AHR (0.47) | KMT2AMEN1MAPTRAB9ABLM | |
| SCHEMBL11842455 | 0.69 | POLB (0.41) | GAAPKMKMT2AMEN1ALDH1A1 | |
| SCHEMBL5791958 | 0.68 | HRH1 (0.38) | PKMALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL11814492 | 0.67 | ALDH1A1 (0.41) | GAAPKMKMT2AMAOAMEN1 | |
| SCHEMBL10953852 | 0.67 | NPC1 (0.46) | KMT2AMEN1MAPTRAB9ABLM | |
| SCHEMBL10955779 | 0.65 | HRH4 (0.34) | GAA | |
| SCHEMBL10780626 | 0.63 | SRD5A1 (0.41) | KMT2AMEN1ALDH1A1MAPTRAB9A | |
| SCHEMBL6987062 | 0.62 | DRD2 (0.46) | MAOA | |
| SCHEMBL3358267 | 0.62 | RNASEH1 (1.00) | RNASEH1GAATLR9PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069353-A1 | POLYCYCLIC AGENTS FOR THE TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS INFECTIONS | BIOTA SCIENTIFIC MANAGEMENT PTY. LTD. (AU) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008037011-A1 | POLYCYCLIC AGENTS FOR THE TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS INFECTIONS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2008-04-03 | — | — | WO | disclosed |