Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4028672 | 0.90 | LMNA (0.30) | — | |
| SCHEMBL4269505 | 0.78 | SMN1; SMN2 (0.33) | KDM4EMAPTVCAM1PDK2SMN1; SMN2 | |
| SCHEMBL4267446 | 0.76 | HTT (0.34) | MAPTVCAM1SMN1; SMN2 | |
| SCHEMBL7495310 | 0.72 | PPARG (0.41) | — | |
| SCHEMBL4274890 | 0.71 | VCAM1 (0.33) | KDM4EMAPTVCAM1SMN1; SMN2HSD17B10 | |
| SCHEMBL27561142 | 0.71 | RAB9A (0.36) | KDM4EMAPTVCAM1PDK2SMN1; SMN2 | |
| SCHEMBL8175098 | 0.71 | GAA (0.42) | KDM4EMAPTVCAM1PDK2SMN1; SMN2 | |
| SCHEMBL7946301 | 0.70 | ACLY (0.44) | KDM4EMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL4273633 | 0.70 | VCAM1 (0.32) | KDM4EMAPTVCAM1PDK2SMN1; SMN2 | |
| SCHEMBL8164153 | 0.70 | EDNRA (0.41) | KDM4EVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045465-B1 | 3-heterocyclyl-substituted benzoyl derivatives | BASF SE (DE) | 2015-06-02 | — | — | US | disclosed |
| US-7608564-B2 | 3-heterocyclyl-substituted benzoyl derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2009-10-27 | — | — | US | disclosed |
| US-20080039327-A1 | Herbicide; in crops such as wheat, rice, maize, soybeans and cotton they act against broad-leaved weeds and grass weeds without damaging the crop plants; compounds are based on 3-(5,5-disubstituted 2-isoxazolin-3-yl)benzoic acid, esters, thioesters and pyrazolyl ketones thereof | DEYN WOLFGANG V | 2008-02-14 | — | — | US | disclosed |
| US-7232792-B2 | 3-heterocyclyl-substituted benzoyl derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-19 | — | — | US | disclosed |
| US-20020025910-A1 | 3-heterocycly1 - substituted benzoyl derivatives | DEYN WOLFGANG VON (DE) | 2002-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020025910-A1 | 3-heterocycly1 - substituted benzoyl derivatives | CBR3, CBR1, RRS1 | KDM4E 2275/4885MITF 4219/4885MAPT 4860/4885 |
| US-20080039327-A1 | Herbicide; in crops such as wheat, rice, maize, soybeans and cotton they act against broad-leaved weeds and grass weeds without damaging the crop plants; compounds are based on 3-(5,5-disubstituted 2-isoxazolin-3-yl)benzoic acid, esters, thioesters and pyrazolyl ketones thereof | CBR3, CBR1, GLRX3 | KDM4E 1856/4885MITF 4748/4885MAPT 4606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.