SCHEMBL7946301

SCHEMBL7946301

COC(=O)c1ccc(S(C)(=O)=O)c(-c2ccccc2)c1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACLY P53396 5/20 0.44
LMNA P02545 3/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA5A P35218 1/20 0.43
CA9 Q16790 1/20 0.43
KMT2A Q03164 5/20 0.41
MEN1 O00255 4/20 0.41
KDM4E B2RXH2 3/20 0.41
MAPT P10636 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPK1 P28482 1/20 0.41
PPARG P37231 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
NR2E3 Q9Y5X4 1/20 0.41
NCOR2 Q9Y618 1/20 0.41
PLA2G2A P14555 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7948238 0.85 LMNA (0.44) ACLYLMNACA1CA2MAPT
SCHEMBL4278676 0.78 VCAM1 (0.40) LMNACA1CA2CA5ACA9
SCHEMBL6990716 0.78 FABP4 (0.47) LMNAKMT2AMEN1KDM4EMAPT
SCHEMBL7627991 0.78 MITF (0.43) LMNACA1CA2CA5ACA9
SCHEMBL4268094 0.78 KDM4E (0.44) LMNACA1CA2CA5ACA9
SCHEMBL7656900 0.77 HSD17B10 (0.43) ACLYLMNACA1CA2CA5A
SCHEMBL7946291 0.77 SMN1; SMN2 (0.44) ACLYLMNAKMT2AMEN1KDM4E
SCHEMBL30230387 0.77 CA1 (0.41) ACLYCA1CA2CA5ACA9
SCHEMBL29182498 0.77 CA2 (0.41) LMNACA1CA2CA5ACA9
SCHEMBL8175098 0.76 GAA (0.42) CA1CA2CA5ACA9KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265606-B1 TO CONTROL A BROAD SPECTRUM OF UNDESIRABLE VEGETATION, ARE SELECTIVE TO MAJOR CROPS, HAVE DESIRABLE ENVIRONMENTAL PROFILES, DOW AGROSCIENCES LLC 2001-07-24 US disclosed
US-6010981-A 1-alkyl-4-benzoyl-5-hydroxypyrazole compounds and their use as herbicides DOW AGROSCIENCES LLC (US) 2000-01-04 US disclosed