Kaempferide

Kaempferide

SCHEMBL426774

COc1ccc(-c2oc3cc(O)cc(O)c3c(=O)c2O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 8/20 1.00
CYP1A1 P04798 7/20 1.00
CYP1B1 Q16678 7/20 1.00
ABCB1 P08183 7/20 1.00
MAOA P21397 5/20 1.00
FTO Q9C0B1 5/20 1.00
CYP3A4 P08684 8/20 0.79
CYP2D6 P10635 6/20 0.79
MEN1 O00255 8/20 0.75
KMT2A Q03164 8/20 0.75
XDH P47989 6/20 0.75
KDM4E B2RXH2 6/20 0.75
IPMK Q8NFU5 5/20 0.75
IP6K2 Q9UHH9 5/20 0.75
MAPT P10636 5/20 0.75
HSD17B10 Q99714 5/20 0.75
CYP2C9 P11712 5/20 0.75
CA12 O43570 4/20 0.75
PPARG P37231 4/20 0.75
CA7 P43166 4/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Kaempferide SCHEMBL29371282 1.00 CYP1A2 (1.00) CYP1A2CYP1A1CYP1B1ABCB1MAOA
SCHEMBL748643 0.93 MAOA (0.90) CYP1A2CYP1A1CYP1B1ABCB1MAOA
Kaempferol SCHEMBL15634534 0.89 MEN1 (0.89) CYP1A2CYP1A1CYP1B1ABCB1MAOA
Kaempferide SCHEMBL19097707 0.89 ABCB1 (0.79) CYP1A2CYP1A1CYP1B1ABCB1MAOA
SCHEMBL12455834 0.88 CYP1A1 (0.79) CYP1A2CYP1A1CYP1B1ABCB1MAOA
Ermanin SCHEMBL2875089 0.88 CYP3A4 (1.00) CYP1A2CYP1A1CYP1B1ABCB1MAOA
Rhamnocitrin SCHEMBL29903288 0.88 MAOA (1.00) CYP1A2CYP1A1CYP1B1ABCB1MAOA
Rhamnocitrin SCHEMBL1759429 0.88 MAOA (1.00) CYP1A2CYP1A1CYP1B1ABCB1MAOA
SCHEMBL5146598 0.88 CYP1A1 (0.79) CYP1A2CYP1A1CYP1B1ABCB1MAOA
SCHEMBL6504199 0.87 CYP1B1 (0.77) CYP1A2CYP1A1CYP1B1ABCB1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2069 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118845751-B Application of kaempferide and/or kaempferide metabolite in preparation of antiviral infection medicine SHANDONG UNIVERSITY OF TRADITIONAL CHINESE MEDICINE (CN) 2026-05-26 CN claimed
CN-122042846-A Ganhaiweikang capsule characteristic spectrum based on multi-component substance basis and construction method and application thereof 陕西科技大学 2026-05-15 CN claimed
CN-122031455-A A plant active ingredient for inhibiting synovial cell inflammatory reaction and its method for treating rheumarthritis 黔东南民族职业技术学院 2026-05-15 CN claimed
EP-3346842-B1 STABLE INOCULANT COMPOSITIONS AND METHODS FOR PRODUCING SAME NOVONESIS PLANT BIOSOLUTIONS AS (DK) 2026-03-25 EP claimed
US-12514278-B2 Tobacco-derived composition R.J. REYNOLDS TOBACCO COMPANY (US) 2026-01-06 US claimed
WO-2025235852-A1 FLAVONOID COMPOSITIONS AND METHODS OF USE SYNGENTA CROP PROTECTION AG (CH) 2025-11-13 WO claimed
CN-115443162-B Drug injection device, system and method 解决方案医疗公司 2025-05-06 CN claimed
CN-119818520-A Application of kaempferide in preparation of non-alcoholic fatty liver disease resistant drugs 江西中医药大学 2025-04-15 CN claimed
CN-119823943-A Combined culture medium of NK cells and culture method of NK cells 湖北万德瑞生命科学技术有限公司 2025-04-15 CN claimed
CN-118584013-B Method for simultaneously determining contents of various components in turbidity-resolving, stagnation-resolving and arthralgia-removing formula based on UHPLC-QqQ-MS/MS technology 福建中医药大学 2025-04-08 CN claimed
WO-2006001665-A1 COMPOSITION FOR PREVENTING OR TREATING ACUTE OR CHRONIC DEGENERATIVE BRAIN DISEASES INCLUDING FLAVONOID DERIVATIVES SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) 2006-01-05 WO claimed
US-6872771-B1 Tire with rubber containing flavone THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-03-29 US claimed
CN-1546483-A Method for extracting high purity seabuckthorn flavone aglycone 水利部沙棘开发管理中心 2004-11-17 CN claimed
EP-1435930-A2 ANTI-GLYCATION AGENTS FOR PREVENTING AGE-, DIABETES-, AND SMOKING-RELATED COMPLICATIONS NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2004-07-14 EP claimed
CN-1511573-A Medicinal composition for preventing and curing prostatitis and hyperplasia of prostate and its preparing method 中国中医药科技开发交流中心 2004-07-14 CN claimed
US-20040057908-A1 Oral compositions and use thereof NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2004-03-25 US claimed
EP-1399119-A2 ORAL COMPOSITIONS AND USE THEREOF University of Rochester (US) 2004-03-24 EP claimed
WO-2003032969-A2 ANTI-GLYCATION AGENTS FOR PREVENTING AGE-, DIABETES-, AND SMOKING-RELATED COMPLICATIONS NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2003-04-24 WO claimed
CN-1371985-A Health care wine containing conjugaed linoleic acid or conjugated linoleic acid derivant XINJIANG INST CHEMISTRY CAS (CN) 2002-10-02 CN claimed
WO-2002047615-A2 ORAL COMPOSITIONS AND USE THEREOF UNIVERSITY OF ROCHESTER (US) 2002-06-20 WO claimed