Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.77 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.77 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.77 |
| ▸ | MAOA | P21397 | 4/20 | 0.77 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.76 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | RECQL | P46063 | 4/20 | 0.64 |
| ▸ | POLH | Q9Y253 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | APEX1 | P27695 | 2/20 | 0.64 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | IP6K2 | Q9UHH9 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Kaempferide SCHEMBL426774 | 0.87 | CYP1A2 (1.00) | CYP1B1CYP1A1CYP1A2ABCB1MAOA | |
| Kaempferide SCHEMBL29371282 | 0.87 | CYP1A2 (1.00) | CYP1B1CYP1A1CYP1A2ABCB1MAOA | |
| Ermanin SCHEMBL2875089 | 0.86 | CYP3A4 (1.00) | CYP1B1CYP1A1CYP1A2ABCB1MAOA | |
| SCHEMBL6502620 | 0.85 | CYP1A1 (0.78) | CYP1B1CYP1A1CYP1A2ABCB1MAOA | |
| SCHEMBL29711182 | 0.85 | CYP1A1 (0.78) | CYP1B1CYP1A1CYP1A2ABCB1MAOA | |
| SCHEMBL6502058 | 0.82 | ABCB1 (0.68) | CYP1B1CYP1A1CYP1A2ABCB1MAOA | |
| SCHEMBL6494662 | 0.82 | MEN1 (0.79) | CYP1B1CYP1A1CYP1A2ABCB1MAOA | |
| SCHEMBL31548920 | 0.81 | CYP3A4 (0.80) | CYP1B1CYP1A1CYP1A2ABCB1MAOA | |
| SCHEMBL748643 | 0.81 | MAOA (0.90) | CYP1B1CYP1A1CYP1A2ABCB1MAOA | |
| SCHEMBL30131217 | 0.80 | CYP3A4 (0.88) | CYP1B1CYP1A1CYP1A2ABCB1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016907-A1 | NOVEL FLAVONE DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2005-02-24 | — | — | WO | disclosed |