Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.85 |
| ▸ | POLB | P06746 | 2/20 | 0.85 |
| ▸ | APEX1 | P27695 | 2/20 | 0.85 |
| ▸ | RECQL | P46063 | 2/20 | 0.85 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.85 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.85 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.79 |
| ▸ | MAOA | P21397 | 3/20 | 0.79 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.79 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.79 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 3/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | MMP1 | P03956 | 1/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.77 |
| ▸ | HTT | P42858 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649968 | 0.94 | CYP3A4 (0.88) | CYP3A4CYP2D6KDM4EPOLBAPEX1 | |
| SCHEMBL30131217 | 0.94 | CYP3A4 (0.88) | CYP3A4CYP2D6KDM4EPOLBAPEX1 | |
| Isokaempferide SCHEMBL29721227 | 0.92 | POLH (1.00) | CYP3A4CYP2D6KDM4EPOLBAPEX1 | |
| Isokaempferide SCHEMBL1628023 | 0.92 | POLH (1.00) | CYP3A4CYP2D6KDM4EPOLBAPEX1 | |
| SCHEMBL31548920 | 0.89 | CYP3A4 (0.80) | CYP3A4CYP2D6KDM4EPOLBAPEX1 | |
| SCHEMBL3188065 | 0.89 | POLH (0.83) | CYP3A4CYP2D6KDM4EPOLBAPEX1 | |
| SCHEMBL11096105 | 0.89 | POLH (0.83) | CYP3A4CYP2D6KDM4EPOLBAPEX1 | |
| SCHEMBL20100899 | 0.89 | CYP3A4 (0.80) | CYP3A4CYP2D6KDM4EPOLBAPEX1 | |
| SCHEMBL15361036 | 0.89 | POLH (0.83) | CYP3A4CYP2D6KDM4EPOLBAPEX1 | |
| SCHEMBL4631662 | 0.88 | ABCB1 (1.00) | CYP3A4CYP2D6KDM4EPOLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240315965-A1 | COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS | Natural Extraction Systems, LLC (US) | 2024-09-26 | — | — | US | claimed |
| US-20230089351-A1 | METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES | Natural Extraction Systems, LLC (US) | 2023-03-23 | — | — | US | claimed |
| US-20220281903-A1 | FLAVONOID DERIVATIVE FOR TREATING DENTAL CARIES | MÜHLBAUER TECHNOLOGY GMBH (DE) | 2022-09-08 | — | — | US | claimed |
| WO-2022182523-A1 | COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES | Natural Extraction Systems, LLC (US) | 2022-09-01 | — | — | WO | claimed |
| WO-2022182527-A1 | COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS | Natural Extraction Systems, LLC (US) | 2022-09-01 | — | — | WO | claimed |
| EP-4017585-A1 | FLAVONOID DERIVATIVE FOR TREATING DENTAL CARIES | Mühlbauer Technology GmbH (DE) | 2022-06-29 | — | — | EP | claimed |
| CN-113768921-A | Application of methoxy flavonoid compound in preparing anti-leucoderma medicament | 张波 | 2021-12-10 | — | — | CN | claimed |
| WO-2021158575-A1 | COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES | Natural Extraction Systems, LLC (US) | 2021-08-12 | — | — | WO | claimed |
| WO-2021158573-A1 | METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES | Natural Extraction Systems, LLC (US) | 2021-08-12 | — | — | WO | claimed |
| WO-2021032844-A1 | FLAVONOID DERIVATIVE FOR TREATING DENTAL CARIES | MÜHLBAUER TECHNOLOGY GMBH (DE) | 2021-02-25 | — | — | WO | claimed |
| US-20040057908-A1 | Oral compositions and use thereof | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2004-03-25 | — | — | US | claimed |
| EP-1399119-A2 | ORAL COMPOSITIONS AND USE THEREOF | University of Rochester (US) | 2004-03-24 | — | — | EP | claimed |
| WO-2002047615-A2 | ORAL COMPOSITIONS AND USE THEREOF | UNIVERSITY OF ROCHESTER (US) | 2002-06-20 | — | — | WO | claimed |
| EP-0290442-A4 | PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS. | CHEMEX PHARMACEUTICALS INC (US) | 1990-07-03 | — | — | EP | claimed |
| EP-0290442-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS | CHEMEX PHARMACEUTICALS, INC. (US) | 1988-11-17 | — | — | EP | claimed |
| US-4774229-A | ANTITUMOR AGENTS, SKIN DISORDERS, CANCER TREATMENT | CHEMEX PHARMACEUTICALS, INC. (US) | 1988-09-27 | — | — | US | claimed |
| WO-1988003805-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS | CHEMEX PHARMACEUTICALS, INC. (US) | 1988-06-02 | — | — | WO | claimed |
| WO-1987006833-A1 | MODIFICATION OF PLANT EXTRACTS FROM ZYGOPHYLLACEAE | CHEMEX PHARMACEUTICALS, INC. (US) | 1987-11-19 | — | — | WO | claimed |
| US-4352792-A | 3-Alkoxyflavone antiviral agents | HOFFMANN-LA ROCHE INC. (US) | 1982-10-05 | — | — | US | claimed |
| EP-0019081-A1 | Flavone derivatives, their preparation, these novel and known flavones as antiviral agents, and pharmaceutical compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1980-11-26 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220281903-A1 | FLAVONOID DERIVATIVE FOR TREATING DENTAL CARIES | ITGA8, ITGAL, ITGB2 | CYP3A4 1785/4885CYP2D6 1816/4885KDM4E 192/4885 |
| US-20230089351-A1 | METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES | FABP2, FABP4, GUSB | CYP3A4 3571/4885CYP2D6 4172/4885KDM4E 4637/4885 |
| US-20040057908-A1 | Oral compositions and use thereof | UGGT1, DPM1, B4GALT1 | CYP3A4 269/4885CYP2D6 419/4885KDM4E 3655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.