Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 3/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5960581 | 0.83 | CDK8 (0.38) | PRNPCYP1A2CYP2C9CYP2C19PPARG | |
| SCHEMBL7121722 | 0.82 | PRNP (0.38) | PRNPCYP1A2CYP2C9CYP2C19PPARG | |
| SCHEMBL27809850 | 0.80 | CCNC (0.40) | PRNPCYP1A2CYP2C9CYP2C19PPARG | |
| SCHEMBL7824673 | 0.79 | LMNA (0.39) | PRNPCYP1A2CYP2C9CYP2C19PPARG | |
| SCHEMBL8877986 | 0.79 | BAZ2B (0.40) | CYP1A2CCNCCDK8ALDH1A1KMT2A | |
| SCHEMBL31502568 | 0.78 | ALDH1A1 (0.42) | CCNCCDK8ALDH1A1KMT2ATDP1 | |
| SCHEMBL1650715 | 0.77 | CYP1A2 (0.49) | CYP1A2CYP2C9CYP2C19ALDH1A1KMT2A | |
| SCHEMBL31427531 | 0.76 | GABRP (0.42) | CYP1A2CYP2C9CYP2C19PPARGHIF1A | |
| SCHEMBL9089075 | 0.75 | NPSR1 (0.32) | PRNPCYP1A2CYP2C9CYP2C19PPARG | |
| SCHEMBL16236499 | 0.74 | CCNC (0.36) | PRNPCYP1A2CYP2C9CYP2C19PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8247392-B2 | Materials for selective trapping of carbon monoxide | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2012-08-21 | — | — | US | disclosed |
| US-7521551-B2 | Chlorins possessing fused ring systems useful as photoselective compounds for photodynamic therapy | MIRAVANT PHARMACEUTICALS, INC. (US) | 2009-04-21 | — | — | US | disclosed |
| US-20080275232-A1 | CHLORINS POSSESSING FUSED RING SYSTEMS USEFUL AS PHOTOSELECTIVE COMPOUNDS FOR PHOTODYNAMIC THERAPY | MIRAVANT PHARMACEUTICALS, INC. | 2008-11-06 | — | — | US | disclosed |
| EP-1414823-B1 | MATERIALS FOR SELECTIVE TRAPPING OF CARBON MONOXIDE | AIR LIQUIDE (FR) | 2007-05-02 | — | — | EP | disclosed |
| US-20060287195-A1 | Novel materials for selective trapping of carbon minixide | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2006-12-21 | — | — | US | disclosed |
| US-20050020560-A1 | Chlorins processing fused ring systems useful as photoselective compounds for photodynamic therapy | MIRAVANT PHARMACEUTICALS, INC. | 2005-01-27 | — | — | US | disclosed |
| US-6794505-B1 | Chlorins possessing fused ring systems useful as photoselective compounds for photodynamic therapy | MIRAVANT PHARMACEUTICALS, INC. | 2004-09-21 | — | — | US | disclosed |
| WO-2001074818-A1 | CHLORINS WITH FUSED RINGS FOR USE IN PHOTODYNAMIC THERAPY | MIRAVANT PHARMACEUTICALS, INC. (US) | 2001-10-11 | — | — | WO | disclosed |
| US-5672717-A | ANTITUMOR AGENTS TREATING CANCER | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1997-09-30 | — | — | US | disclosed |
| US-5554764-A | DIPYRROMETHANES ARE CLAIMED. | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1996-09-10 | — | — | US | disclosed |
| US-5446166-A | Reacting isocyanoacetate with prophosphatrane and acyl halide or acid anhydride | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1995-08-29 | — | — | US | disclosed |
| US-5367084-A | Preparation of pyrrol and oxazole compounds: formation of porphyrins and c-acyl-α-amino acid esters therefrom | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1994-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275232-A1 | CHLORINS POSSESSING FUSED RING SYSTEMS USEFUL AS PHOTOSELECTIVE COMPOUNDS FOR PHOTODYNAMIC THERAPY | PPOX, HMBS, DDT | PRNP 4560/4885CYP1A2 973/4885CYP2C9 504/4885 |
| US-20060287195-A1 | Novel materials for selective trapping of carbon minixide | CBR1, CBR3, FOXM1 | PRNP 3497/4885CYP1A2 917/4885CYP2C9 620/4885 |
| US-20050020560-A1 | Chlorins processing fused ring systems useful as photoselective compounds for photodynamic therapy | PPOX, HMBS, DDT | PRNP 4513/4885CYP1A2 901/4885CYP2C9 476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.