Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17440402 | 0.94 | ELANE (0.40) | ELANEMAPK8SCN9AF10MEN1 | |
| SCHEMBL4272019 | 0.81 | ALDH1A1 (0.47) | MAPK8SCN9AF10MEN1KMT2A | |
| SCHEMBL15924716 | 0.81 | MAPK8 (0.52) | ELANEMAPK8MEN1KMT2AGAA | |
| SCHEMBL30411682 | 0.77 | L3MBTL1 (0.49) | MAPK8F10MEN1KMT2AGAA | |
| SCHEMBL2329194 | 0.74 | MAPK8 (0.50) | ELANEMAPK8KMT2AGAARAB9A | |
| SCHEMBL9120208 | 0.73 | SCN9A (0.49) | MAPK8SCN9AMEN1KMT2AGAA | |
| SCHEMBL3706881 | 0.72 | DRD1 (0.43) | RAB9ASMN1; SMN2TDP1DRD1HTR1A | |
| SCHEMBL17440403 | 0.71 | PIN1 (0.44) | SCN9AMEN1KMT2AGAANPC1 | |
| SCHEMBL190518 | 0.71 | PLAAT3 (0.48) | MEN1KMT2AGAANPC1RAB9A | |
| SCHEMBL667594 | 0.70 | MEN1 (0.64) | MAPK8MEN1KMT2AGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3169676-A1 | BIS(ARYL)CATECHOL DERIVATIVES AS HERBICIDES | E. I. du Pont de Nemours and Company (US) | 2017-05-24 | — | — | EP | disclosed |
| WO-2016010731-A1 | BIS(ARYL)CATECHOL DERIVATIVES AS HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2016-01-21 | — | — | WO | disclosed |