Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | DPYD | Q12882 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4273433 | 0.80 | DPYD (0.31) | DPYD | |
| SCHEMBL152547 | 0.78 | ADORA2B (0.45) | ADORA2BADORA3ADORA2A | |
| SCHEMBL153254 | 0.77 | ADRB1 (0.45) | — | |
| SCHEMBL26948740 | 0.68 | ADORA2B (0.44) | ADORA2BADORA3ADORA2A | |
| Uracil SCHEMBL28379047 | 0.67 | CRBN (0.49) | — | |
| SCHEMBL6028163 | 0.66 | ADORA2B (0.44) | ADORA2BADORA3ADORA2A | |
| SCHEMBL7133034 | 0.65 | ATAD2 (0.47) | DPYD | |
| SCHEMBL26948707 | 0.64 | KMT2A (0.51) | ADORA2BADORA3ADORA2A | |
| SCHEMBL7598099 | 0.63 | ATAD2 (0.41) | — | |
| SCHEMBL175877 | 0.62 | DPYD (0.52) | DPYD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009126727-A1 | RNA COMPOSITIONS FOR MODULATING IMMUNE RESPONSE | ALNYLAM PHARMACEUTICALS, INC. (US) | 2009-10-15 | — | — | WO | disclosed |