Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPYD | Q12882 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4273436 | 0.80 | ADORA2B (0.34) | DPYD | |
| SCHEMBL148953 | 0.78 | CYP3A4 (0.37) | — | |
| SCHEMBL153254 | 0.77 | ADRB1 (0.45) | — | |
| SCHEMBL12410891 | 0.68 | TK1 (0.41) | — | |
| Uracil SCHEMBL28379047 | 0.67 | CRBN (0.49) | — | |
| SCHEMBL12410794 | 0.65 | TK1 (0.42) | — | |
| SCHEMBL7133034 | 0.65 | ATAD2 (0.47) | DPYD | |
| SCHEMBL9021896 | 0.64 | TK1 (0.56) | — | |
| SCHEMBL7598099 | 0.63 | ATAD2 (0.41) | — | |
| SCHEMBL27627581 | 0.63 | ATAD2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009126727-A1 | RNA COMPOSITIONS FOR MODULATING IMMUNE RESPONSE | ALNYLAM PHARMACEUTICALS, INC. (US) | 2009-10-15 | — | — | WO | disclosed |