Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | CA7 | P43166 | 3/20 | 0.51 |
| ▸ | CA9 | Q16790 | 3/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684319 | 0.84 | MAPT (0.77) | HSD17B2MAPTALDH1A1MAPK1CA12 | |
| SCHEMBL4273797 | 0.83 | HSD17B2 (0.55) | HSD17B2MAPTALDH1A1MAPK1CA12 | |
| SCHEMBL23876967 | 0.81 | ALDH1A1 (0.59) | HSD17B2MAPTALDH1A1MAPK1CA12 | |
| SCHEMBL7093941 | 0.81 | ALDH1A1 (0.62) | HSD17B2MAPTALDH1A1MAPK1CA12 | |
| SCHEMBL11341115 | 0.80 | MAPT (0.61) | HSD17B2MAPTALDH1A1MAPK1CA12 | |
| SCHEMBL30506315 | 0.79 | HSD17B2 (0.76) | HSD17B2MAPTALDH1A1MAPK1CA12 | |
| SCHEMBL1660365 | 0.79 | HSD17B2 (0.76) | HSD17B2MAPTALDH1A1MAPK1CA12 | |
| SCHEMBL3470599 | 0.78 | MAPT (0.64) | MAPTALDH1A1MAPK1CA12CA1 | |
| SCHEMBL16605589 | 0.77 | MAPT (0.57) | HSD17B2MAPTALDH1A1MAPK1CA12 | |
| SCHEMBL9005554 | 0.76 | HSD17B2 (0.70) | HSD17B2MAPTALDH1A1MAPK1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106916067-A | The preparation method of hydrochloric acid Erlotinib key intermediate | 江苏豪森药业集团有限公司 | 2017-07-04 | — | — | CN | claimed |
| CN-106916067-B | Preparation method of erlotinib hydrochloride key intermediate | 江苏豪森药业集团有限公司 | 2021-07-06 | — | — | CN | disclosed |
| CN-106916067-A | The preparation method of hydrochloric acid Erlotinib key intermediate | 江苏豪森药业集团有限公司 | 2017-07-04 | — | — | CN | disclosed |
| US-20100267949-A1 | Method of Synthesizing 6,7-Substituted 4-Anilino Quinazoline | OMEGA MEDICAL TAIWAN LIMITED (TW) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267949-A1 | Method of Synthesizing 6,7-Substituted 4-Anilino Quinazoline | NQO2, ATIC, CYP3A7 | HSD17B2 2078/4885MAPT 3826/4885ALDH1A1 878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.