Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
| ▸ | FDPS | P14324 | 3/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4263651 | 0.95 | LMNA (0.42) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL4261190 | 0.93 | DNM1 (0.46) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL2347365 | 0.93 | DNM1 (0.46) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL18007368 | 0.93 | OPRM1 (0.42) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL3899908 | 0.90 | DNM1 (0.36) | LMNADNM1TSHRFDPS | |
| SCHEMBL1582227 | 0.90 | DNM1 (0.42) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL1582541 | 0.85 | DNM1 (0.39) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL3891523 | 0.84 | — | — | |
| SCHEMBL7799148 | 0.83 | OPRM1 (0.39) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL21232740 | 0.82 | LMNA (0.52) | LMNATSHRSMPD1SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399570-B2 | Functionalized polymers and improved tires therefrom | BRIDGESTONE CORPORATION (JP) | 2013-03-19 | — | — | US | disclosed |
| US-20090326161-A1 | FUNCTIONALIZED POLYMERS AND IMPROVED TIRES THEREFROM | BRIDGESTONE CORPORATION (JP) | 2009-12-31 | — | — | US | disclosed |
| US-7598322-B1 | particularly tire treads exhibiting reduced rolling resistance; a vulcanized rubbery polymer such as polybutadiene-butadiene-styrene copolymer made from living polymerization using butyllithium initiator and a tributyloxyborane as polymerization terminator | BRIDGESTONE CORPORATION (JP) | 2009-10-06 | — | — | US | disclosed |