SCHEMBL1582227

SCHEMBL1582227

BOC(CCCC)CCCCC

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.42
OPRM1 P35372 1/20 0.40
LMNA P02545 1/20 0.37
CA2 P00918 1/20 0.35
TSHR P16473 1/20 0.35
THRB P10828 1/20 0.35
FDPS P14324 3/20 0.34
SMPD1 P17405 3/20 0.34
GPR84 Q9NQS5 2/20 0.33
ZDHHC7 Q9NXF8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4261190 0.97 DNM1 (0.46) DNM1OPRM1LMNACA2TSHR
SCHEMBL2347365 0.97 DNM1 (0.46) DNM1OPRM1LMNACA2TSHR
SCHEMBL18007368 0.97 OPRM1 (0.42) DNM1OPRM1LMNATSHRTHRB
SCHEMBL4263651 0.95 LMNA (0.42) DNM1OPRM1LMNATSHRTHRB
SCHEMBL1582541 0.95 DNM1 (0.39) DNM1OPRM1LMNACA2TSHR
SCHEMBL4274138 0.90 LMNA (0.39) DNM1OPRM1LMNATSHRTHRB
SCHEMBL3899908 0.90 DNM1 (0.36) DNM1LMNACA2TSHRFDPS
SCHEMBL7799148 0.87 OPRM1 (0.39) DNM1OPRM1LMNATSHRTHRB
SCHEMBL4263383 0.84
SCHEMBL21232740 0.81 LMNA (0.52) LMNATSHRSMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1375485-B1 METHOD FOR PREPARING 7-QUINOLINYL-3,5-DIHYDROXYHEPT-6-ENOATE NISSAN CHEMICAL IND LTD (JP) 2011-04-20 EP disclosed
US-7038056-B2 Method for preparing a 7-quinolinyl-3,5-dihydroxyhept-6-enoate NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2006-05-02 US disclosed
US-20050014947-A1 Method for preparing a 7-quinolinyl-3, 5-dihydroxyhept-6-enoate NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2005-01-20 US disclosed
EP-1375485-A1 METHOD FOR PREPARING 7-QUINOLINYL-3,5-DIHYDROXYHEPT-6-ENOATE Nissan Chemical Industries, Ltd. (JP) 2004-01-02 EP disclosed
EP-0519496-B1 Thermosetting copolymers, silicon carbide-based fiber and processes for producing same TONEN CORP (JP) 1996-05-22 EP disclosed
EP-0404503-B1 Boron-containing, silicon nitride-based ceramic shaped body production process TONEN CORP (JP) 1996-03-06 EP disclosed
EP-0389084-B1 Process for producing a polyborosilazane TONEN CORP (JP) 1995-09-20 EP disclosed
EP-0415704-B1 Catalysts for polymerization of olefins CHISSO CORP (JP) 1995-05-10 EP disclosed
US-5292830-A Silane, silazane, boron block crosslinked copolymers TONEN CORPORATION (JP) 1994-03-08 US disclosed
EP-0519496-A1 Thermosetting copolymers, silicon carbide-based fiber and processes for producing same Tonen Corporation (JP) 1992-12-23 EP disclosed
US-5128286-A BORON-CONTAINING, SILICON NITRIDE-BASED CERAMIC SHAPED BODY TONEN CORPORATION (JP) 1992-07-07 US disclosed
US-5122490-A Composed of organomagesium compounds, titanium and vanadium halides, alcohols, halogenated silanes, siloxanes, borates, electron donors and cyclic ether CHISSO CORPORATION (JP) 1992-06-16 US disclosed
US-5084429-A Coordination catalysts for olefin polymerization from magnesium, titanium, vanadium and silicon compounds CHISSO CORPORATION (JP) 1992-01-28 US disclosed
US-5030744-A Polyborosilazane and process for producing same TONEN CORPORATION (JP) 1991-07-09 US disclosed
EP-0415704-A2 Catalysts for polymerization of olefins CHISSO CORPORATION (JP) 1991-03-06 EP disclosed
EP-0404503-A1 Boron-containing, silicon nitride-based ceramic shaped body production process Tonen Corporation (JP) 1990-12-27 EP disclosed
EP-0389084-A2 Process for producing a polyborosilazane Tonen Corporation (JP) 1990-09-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050014947-A1 Method for preparing a 7-quinolinyl-3, 5-dihydroxyhept-6-enoate QDPR, DHCR7, GHRHR DNM1 3268/4885OPRM1 1768/4885LMNA 4511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.