Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | FDPS | P14324 | 4/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4263383 | 0.92 | — | — | |
| SCHEMBL18007368 | 0.90 | OPRM1 (0.42) | OPRM1LMNADNM1FDPSSMPD1 | |
| SCHEMBL4263651 | 0.87 | LMNA (0.42) | OPRM1LMNADNM1FDPSSMPD1 | |
| SCHEMBL1582227 | 0.87 | DNM1 (0.42) | OPRM1LMNADNM1FDPSSMPD1 | |
| SCHEMBL2347365 | 0.85 | DNM1 (0.46) | OPRM1LMNADNM1FDPSSMPD1 | |
| SCHEMBL4261190 | 0.85 | DNM1 (0.46) | OPRM1LMNADNM1FDPSSMPD1 | |
| SCHEMBL4274138 | 0.83 | LMNA (0.39) | OPRM1LMNADNM1FDPSSMPD1 | |
| SCHEMBL1582541 | 0.81 | DNM1 (0.39) | OPRM1LMNADNM1FDPSTSHR | |
| SCHEMBL1165052 | 0.81 | — | — | |
| SCHEMBL21232740 | 0.79 | LMNA (0.52) | LMNASMPD1TSHRSPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808849-B1 | Process for the production of ethylenic polymers | SHOWA DENKO KK (JP) | 2001-12-19 | — | — | EP | disclosed |
| US-6011127-A | CATALYST COMPRISING A CHROMIUM COMPOUND, AN ALUMOXANE AND AN ORGANOMETALLIC ALKOXIDE AND/OR ORGANOMETALLIC SILOXIDE AND A CARRIER SUPPORTING THEREON THESE COMPOUNDS. | SHOWA DENKO K.K. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0808849-A1 | Process for the production of ethylenic polymers | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1997-11-26 | — | — | EP | disclosed |