SCHEMBL4275097

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4274753	0.90	CACNA1I (0.46)	CACNA1IKCNH2CACNA1HCYP2D6KDM1A
	SCHEMBL20056105	0.85	CACNA1I (0.49)	CACNA1IKCNH2CACNA1HCYP2D6KDM1A
	SCHEMBL20056421	0.85	CACNA1I (0.48)	CACNA1IKCNH2CACNA1HCYP2D6KDM1A
	SCHEMBL4272977	0.84	CACNA1I (0.52)	CACNA1IKCNH2CACNA1HCYP2D6KDM1A
	SCHEMBL4274989	0.84	CCR2 (0.56)	CACNA1IKCNH2HDAC6HDAC4
	SCHEMBL4280194	0.83	KCNH2 (0.67)	CACNA1IKCNH2CACNA1HCYP2D6
	SCHEMBL4274691	0.82	CACNA1I (0.46)	CACNA1IKCNH2CACNA1HCYP2D6KDM1A
	SCHEMBL4277778	0.82	HTR4 (0.56)	CACNA1IKCNH2CACNA1HCYP2D6HTR4
	SCHEMBL4280558	0.82	CACNA1I (0.66)	CACNA1IKCNH2CACNA1HCYP2D6HDAC6
	SCHEMBL4284138	0.82	KCNH2 (0.60)	CACNA1IKCNH2CACNA1HCYP2D6KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.