Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 16/20 | 0.62 |
| ▸ | OPRL1 | P41146 | 14/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13733764 | 0.85 | OPRM1 (0.62) | OPRM1OPRL1OPRK1 | |
| Hydrochloric Acid SCHEMBL3401730 | 0.84 | OPRM1 (0.60) | OPRM1OPRL1OPRK1 | |
| SCHEMBL27854074 | 0.84 | OPRL1 (0.60) | OPRM1OPRL1OPRK1 | |
| SCHEMBL23718995 | 0.83 | NPC1 (0.60) | OPRM1OPRL1OPRK1OPRD1 | |
| SCHEMBL28026560 | 0.82 | KMT2A (0.54) | OPRM1OPRL1LMNA | |
| SCHEMBL23719016 | 0.82 | OPRM1 (0.52) | OPRM1OPRL1OPRK1 | |
| SCHEMBL18793811 | 0.81 | OPRM1 (0.66) | OPRM1OPRL1OPRK1BLMLMNA | |
| SCHEMBL10760411 | 0.81 | OPRM1 (0.66) | OPRM1OPRL1OPRK1BLMLMNA | |
| SCHEMBL23719096 | 0.81 | ME2 (0.54) | OPRM1OPRL1OPRK1 | |
| SCHEMBL18068774 | 0.79 | OPRM1 (0.62) | OPRM1OPRK1BLMLMNAOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | SULT2A1, STS, SULT1A1 | OPRM1 2798/4885OPRL1 2189/4885OPRK1 2548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.