SCHEMBL4276502

SCHEMBL4276502

C=C(CCSCC)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
HSD17B10 Q99714 2/20 0.39
LMNA P02545 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TET2 Q6N021 4/20 0.37
TET3 O43151 1/20 0.37
TET1 Q8NFU7 1/20 0.37
GRIK1 P39086 1/20 0.35
GRIK2 Q13002 1/20 0.35
GRM1 Q13255 1/20 0.35
GRM2 Q14416 1/20 0.35
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2523047 0.87 TSHR (0.63) TSHRHSD17B10LMNAKMT2ATDP1
SCHEMBL11123745 0.85 HSD17B10 (0.52) TSHRHSD17B10LMNAKMT2ATDP1
SCHEMBL9069775 0.85 TSHR (0.55) TSHRHSD17B10KMT2ATDP1TET2
SCHEMBL11604256 0.81 HSD17B10 (0.42) TSHRHSD17B10LMNAKMT2ATDP1
SCHEMBL11652342 0.78 ALOX5 (0.40) HSD17B10LMNAKMT2ATDP1TET2
SCHEMBL8769768 0.78 THRB (0.53) TSHRHSD17B10KMT2ATDP1ALDH1A1
SCHEMBL7062182 0.78 THRB (0.53) TSHRHSD17B10KMT2ATDP1ALDH1A1
SCHEMBL4415202 0.76
SCHEMBL4957174 0.76
SCHEMBL722524 0.76 TSHR (0.54) TSHRHSD17B10LMNAKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0683174-B1 Thioether containing photopolymerizable compositions EASTMAN KODAK CO (US) 1998-08-05 EP claimed
US-5532286-A BONDING STRENGTH EASTMAN KODAK COMPANY (US) 1996-07-02 US claimed
US-5518789-A ACRYLIC ESTER OR AMIDE, OPTICAL RECORDING EASTMAN KODAK COMPANY (US) 1996-05-21 US claimed
EP-0683174-A2 Thioether containing photopolymerizable compositions EASTMAN KODAK COMPANY (US) 1995-11-22 EP claimed
US-11413905-B2 Tire rubber composition THE YOKOHAMA RUBBER CO., LTD. (JP) 2022-08-16 US disclosed
EP-3459998-B1 TIRE RUBBER COMPOSITION YOKOHAMA RUBBER CO LTD (JP) 2021-12-01 EP disclosed
US-20200316995-A1 Tire Rubber Composition THE YOKOHAMA RUBBER CO., LTD. (JP) 2020-10-08 US disclosed
EP-3459998-A9 TIRE RUBBER COMPOSITION The Yokohama Rubber Co., Ltd. (JP) 2019-07-10 EP disclosed
US-10251392-B2 Antimicrobial devices and compositions AVENT, INC. (US) 2019-04-09 US disclosed
EP-3459998-A1 TIRE RUBBER COMPOSITION The Yokohama Rubber Co., Ltd. (JP) 2019-03-27 EP disclosed
US-20090035342-A1 Antimicrobial Devices and Compositions AVANOS MEDICAL SALES, LLC 2009-02-05 US disclosed
EP-1781098-A2 ANTIMICROBIAL DEVICES AND COMPOSITIONS ACRYMED, INC. (US) 2007-05-09 EP disclosed
WO-2006015317-A2 ANTIMICROBIAL DEVICES AND COMPOSITIONS ACRYMED, INC. (US) 2006-02-09 WO disclosed
EP-0762197-B1 Photographic recording material AGFA GEVAERT AG (DE) 2000-01-12 EP disclosed
US-5587279-A HIGH CONCENTRATION OF SILVER CHLORIDE GRAINS FUJI PHOTO FILM CO., LTD. (JP) 1996-12-24 US disclosed
EP-0666498-A2 Silver halide photographic material Agfa-Gevaert AG (DE) 1995-08-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10251392-B2 Antimicrobial devices and compositions AAAS, AOC1, COL14A1 TSHR 4664/4885HSD17B10 332/4885LMNA 4430/4885
US-20090035342-A1 Antimicrobial Devices and Compositions AAAS, AOC1, COL14A1 TSHR 4664/4885HSD17B10 332/4885LMNA 4430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.