Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13661121 | 0.90 | ALDH1A1 (0.66) | ALDH1A1TDP1SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL4574548 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TDP1SMN1; SMN2SIGMAR1DNM1 | |
| SCHEMBL2929473 | 0.78 | ALDH1A1 (0.81) | ALDH1A1TDP1SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL10223654 | 0.78 | ALDH1A1 (0.74) | ALDH1A1TDP1SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL4283848 | 0.78 | ALDH1A1 (0.81) | ALDH1A1TDP1SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL4578358 | 0.78 | ALDH1A1 (0.81) | ALDH1A1TDP1SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL31622466 | 0.78 | DNM1 (0.42) | ALDH1A1TDP1SMN1; SMN2L3MBTL1SIGMAR1 | |
| SCHEMBL2875261 | 0.77 | ALDH1A1 (0.72) | ALDH1A1TDP1SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL22170168 | 0.76 | ALDH1A1 (0.70) | ALDH1A1TDP1SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL4579798 | 0.76 | ALDH1A1 (0.77) | ALDH1A1TDP1SMN1; SMN2L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131246-A1 | SORDARIN DERIVATIVES FOR PREVENTING OR TREATING INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS | ASTELLAS PHARMA INC. (JP) | 2009-10-29 | — | — | WO | disclosed |
| WO-2009131246-A1 | SORDARIN DERIVATIVES FOR PREVENTING OR TREATING INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS | ASTELLAS PHARMA INC. (JP) | 2009-10-29 | — | — | WO | disclosed |