Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4291881 | 0.91 | SLC6A3 (0.40) | HCRTR1HCRTR2HSD11B1 | |
| SCHEMBL4291623 | 0.91 | HCRTR2 (0.41) | HTR2AHTR2CHTR2BHCRTR2HSD11B1 | |
| SCHEMBL4285848 | 0.86 | SLC6A2 (0.42) | HCRTR1HCRTR2HSD11B1BTKHRH3 | |
| SCHEMBL4288935 | 0.85 | TSHR (0.39) | HSD11B1 | |
| SCHEMBL4285491 | 0.84 | KMT2A (0.41) | SLC9A1HCRTR2HRH3 | |
| SCHEMBL4292808 | 0.81 | SLC6A3 (0.45) | — | |
| SCHEMBL4280120 | 0.80 | LMNA (0.40) | HTR2AHTR2CHTR2BSLC9A1HCRTR1 | |
| SCHEMBL4294068 | 0.79 | POLB (0.36) | HSD11B1BTK | |
| SCHEMBL4282253 | 0.79 | TACR1 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL4282511 | 0.78 | HSD17B10 (0.46) | HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009072643-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-11 | — | — | WO | disclosed |