Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 6/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4285491 | 0.82 | KMT2A (0.41) | HCRTR2 | |
| SCHEMBL4291881 | 0.79 | SLC6A3 (0.40) | HCRTR2RIPK1HCRTR1 | |
| SCHEMBL4282256 | 0.79 | HCRTR2 (0.43) | TACR1OPRL1HCRTR2RIPK1GRM5 | |
| SCHEMBL4280118 | 0.79 | HTR2A (0.40) | HCRTR2HCRTR1 | |
| SCHEMBL4291623 | 0.76 | HCRTR2 (0.41) | HCRTR2 | |
| SCHEMBL4288935 | 0.75 | TSHR (0.39) | NPSR1 | |
| SCHEMBL4285848 | 0.74 | SLC6A2 (0.42) | HCRTR2HCRTR1 | |
| SCHEMBL4281406 | 0.74 | KDM4E (0.36) | NPSR1 | |
| SCHEMBL4294068 | 0.72 | POLB (0.36) | — | |
| SCHEMBL4292808 | 0.71 | SLC6A3 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009072643-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-11 | — | — | WO | disclosed |