Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.54 |
| ▸ | CTSS | P25774 | 4/20 | 0.53 |
| ▸ | CTSK | P43235 | 4/20 | 0.53 |
| ▸ | CTSL | P07711 | 3/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11685409 | 0.92 | CTSL (0.56) | TACR1CTSSCTSKCTSLCTSB | |
| SCHEMBL8894483 | 0.92 | TACR1 (0.54) | TACR1CTSSCTSKCTSLCTSB | |
| SCHEMBL4828679 | 0.88 | CTSL (0.62) | TACR1CTSSCTSKCTSLCTSB | |
| SCHEMBL28723295 | 0.88 | CTSL (0.62) | TACR1CTSSCTSKCTSLCTSB | |
| SCHEMBL28518198 | 0.88 | TACR1 (0.53) | TACR1CTSSCTSKCTSLCTSB | |
| SCHEMBL8387978 | 0.85 | FOLH1 (0.65) | CTSSCTSKCTSLPPARAPPARG | |
| SCHEMBL10421088 | 0.85 | FOLH1 (0.62) | TACR1CTSSCTSKCTSLPPARA | |
| SCHEMBL1796250 | 0.84 | CTSL (0.65) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL2487005 | 0.84 | CTSL (0.65) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL1701581 | 0.84 | CTSL (0.65) | CTSSCTSKCTSLCTSBPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3034607-B1 | PROTEASE SCREENING METHODS AND PROTEASES IDENTIFIED THEREBY | CATALYST BIOSCIENCES INC (US) | 2019-03-27 | — | — | EP | disclosed |
| EP-3034607-A1 | PROTEASE SCREENING METHODS AND PROTEASES IDENTIFIED THEREBY | Catalyst Biosciences, Inc. (US) | 2016-06-22 | — | — | EP | disclosed |
| EP-2402437-B1 | Protease screening methods and proteases identified thereby | CATALYST BIOSCIENCES INC (US) | 2016-06-01 | — | — | EP | disclosed |
| US-9290757-B2 | Protease screening methods and proteases identified thereby | CATALYST BIOSCIENCES, INC. (US) | 2016-03-22 | — | — | US | disclosed |
| US-8663633-B2 | Protease screening methods and proteases identified thereby | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 2014-03-04 | — | — | US | disclosed |
| US-20130164820-A9 | PROTEASE SCREENING METHODS AND PROTEASES IDENTIFIED THEREBY | Torrey Pines Institute For Molecular Studies and Catalyst Biosciences, Inc. | 2013-06-27 | — | — | US | disclosed |
| US-20120308551-A1 | Protease screening methods and proteases identified thereby | Torrey Pines Institute For Molecular Studies and Catalyst Biosciences, Inc. | 2012-12-06 | — | — | US | disclosed |
| US-20120301945-A1 | PROTEASE SCREENING METHODS AND PROTEASES IDENTIFIED THEREBY | Molecular Studies and Catalyst Biosciences, Inc. | 2012-11-29 | — | — | US | disclosed |
| US-8211428-B2 | Protease screening methods and proteases identified thereby | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 2012-07-03 | — | — | US | disclosed |
| US-20090123452-A1 | Protease screening methods and proteases identified thereby | VERTEX PHARMACEUTICALS INCORPORATED | 2009-05-14 | — | — | US | disclosed |
| EP-2046951-A2 | PROTEASE SCREENING METHODS AND PROTEASES INDENTIFIED THERERBY | Catalyst Biosciences, Inc. (US) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008045148-A9 | PROTEASE SCREENING METHODS AND PROTEASES IDENTIFIED THEREBY | CATALYST BIOSCIENCES INC (US) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008045148-A2 | PROTEASE SCREENING METHODS AND PROTEASES IDENTIFIED THEREBY | CATALYST BIOSCIENCES, INC. (US) | 2008-04-17 | — | — | WO | disclosed |
| US-5747499-A | CYCLOPENTAQUINAZOLINE COMPOUNDS CYCLOPENTAQUINAZOLINE COMPOUNDS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1998-05-05 | — | — | US | disclosed |
| EP-0268377-B1 | GLUTAMIC ACID DERIVATIVES, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-03-18 | — | — | EP | disclosed |
| EP-0160252-A2 | Antibacterial compounds | Takeda Chemical Industries, Ltd. (JP) | 1985-11-06 | — | — | EP | disclosed |