Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.54 |
| ▸ | CTSS | P25774 | 7/20 | 0.53 |
| ▸ | CTSL | P07711 | 7/20 | 0.53 |
| ▸ | CTSK | P43235 | 5/20 | 0.53 |
| ▸ | CTSB | P07858 | 4/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4280404 | 0.92 | TACR1 (0.54) | TACR1CTSSCTSLCTSKCTSB | |
| SCHEMBL10523880 | 0.86 | TACR1 (0.56) | TACR1CTSSCTSLCTSKCTSB | |
| SCHEMBL6059278 | 0.84 | CTSK (0.54) | TACR1CTSSCTSLCTSKCTSB | |
| SCHEMBL7215503 | 0.84 | CTSK (0.54) | TACR1CTSSCTSLCTSKCTSB | |
| SCHEMBL11685409 | 0.84 | CTSL (0.56) | TACR1CTSSCTSLCTSKCTSB | |
| SCHEMBL7363415 | 0.83 | SIRT2 (0.59) | TACR1CTSSCTSLCTSKCTSB | |
| SCHEMBL2921260 | 0.83 | FOLH1 (0.59) | TACR1CTSSCTSLCTSKCTSB | |
| SCHEMBL22144256 | 0.83 | CTSK (0.53) | TACR1CTSSCTSLCTSKCTSB | |
| SCHEMBL22144261 | 0.83 | CTSK (0.66) | TACR1CTSSCTSLCTSKCTSB | |
| SCHEMBL17860731 | 0.83 | CTSK (0.53) | TACR1CTSSCTSLCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633232-A | ANALGESIC, ANTIHISTAMINE, SKIN DISORDERS, VISION DEFECTS,ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-27 | — | — | US | disclosed |
| US-5420297-A | Antiinflammatory agents, ophthalmic and antiarthritic agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0394989-B1 | Peptide compounds, process for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-12-21 | — | — | EP | disclosed |
| WO-1994020126-A1 | USE OF PEPTIDES FOR THE MANUFACTURE OF A MEDICAMENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-15 | — | — | WO | disclosed |
| EP-0590152-A1 | PEPTIDES WITH TACHYKININ ANTAGONIST ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-06 | — | — | EP | disclosed |
| WO-1992022569-A1 | PEPTIDES WITH TACHYKININ ANTAGONIST ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-12-23 | — | — | WO | disclosed |
| US-5164372-A | Treatment of respiratory disorders, inflammation, dermatitis | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-11-17 | — | — | US | disclosed |
| EP-0394989-A2 | Peptide compounds, process for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |