Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 13/20 | 0.62 |
| ▸ | CTSS | P25774 | 12/20 | 0.62 |
| ▸ | CTSB | P07858 | 7/20 | 0.62 |
| ▸ | CTSK | P43235 | 4/20 | 0.62 |
| ▸ | TACR1 | P25103 | 1/20 | 0.60 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28723295 | 1.00 | CTSL (0.62) | CTSLCTSSCTSBCTSKTACR1 | |
| SCHEMBL7544219 | 0.93 | CTSS (0.65) | CTSLCTSSCTSBCTSKTACR1 | |
| SCHEMBL10385980 | 0.90 | CTSS (0.62) | CTSLCTSSCTSBCTSKTACR1 | |
| SCHEMBL8619373 | 0.90 | CTSS (0.62) | CTSLCTSSCTSBCTSKTACR1 | |
| SCHEMBL581315 | 0.88 | CTSS (0.52) | CTSLCTSSCTSBCTSKTACR1 | |
| SCHEMBL4280404 | 0.88 | TACR1 (0.54) | CTSLCTSSCTSBCTSKTACR1 | |
| SCHEMBL1479621 | 0.87 | CTSS (0.61) | CTSLCTSSCTSBCTSKTACR1 | |
| SCHEMBL28518198 | 0.86 | TACR1 (0.53) | CTSLCTSSCTSBCTSKTACR1 | |
| SCHEMBL6560581 | 0.86 | CTSS (0.64) | CTSLCTSSCTSBCTSKTACR1 | |
| SCHEMBL6560575 | 0.86 | CTSS (0.64) | CTSLCTSSCTSBCTSKTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624011-A | Preparation method of L-pyroglutamic acid-14C | 长沙贝塔医药科技有限公司 | 2024-03-01 | — | — | CN | claimed |
| CN-117624011-A | Preparation method of L-pyroglutamic acid-14C | 长沙贝塔医药科技有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-117624011-A | Preparation method of L-pyroglutamic acid-14C | 长沙贝塔医药科技有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-110520413-B | Macrocyclic broad spectrum antibiotics | 阿奇克斯制药公司 | 2023-02-17 | — | — | CN | disclosed |
| CN-108884058-B | Macrocyclic broad spectrum antibiotics | 阿奇克斯制药公司 | 2022-04-29 | — | — | CN | disclosed |
| US-8791103-B2 | Carboxylic acid amides, the preparation thereof and their use as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-07-29 | — | — | US | disclosed |
| US-20130237522-A1 | CARBOXYLIC ACID AMIDES, THE PREPARATION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-09-12 | — | — | US | disclosed |
| US-8445525-B2 | Carboxylic acid amides, the preparation thereof and their use as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-05-21 | — | — | US | disclosed |
| US-20080146539-A1 | NEW CARBOXYLIC ACID AMIDES, THE PREPARATION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-06-19 | — | — | US | disclosed |
| US-7371743-B2 | Carboxylic acid amides, the preparation thereof and their use as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-05-13 | — | — | US | disclosed |
| US-5747499-A | CYCLOPENTAQUINAZOLINE COMPOUNDS CYCLOPENTAQUINAZOLINE COMPOUNDS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1998-05-05 | — | — | US | disclosed |
| US-5744612-A | Process for preparation of 5- substituted tetrazoles | TOYO KASEI KOGYO COMPANY LIMITED (JP) | 1998-04-28 | — | — | US | disclosed |
| EP-0796852-A1 | Process for preparation of 5-substituted tetrazoles | Toyo Kasei Kogyo Company Limited (JP) | 1997-09-24 | — | — | EP | disclosed |
| EP-0667864-B1 | TRICYCLIC COMPOUNDS WITH PHARMACEUTICAL ACTIVITY | ZENECA LTD (GB) | 1997-09-24 | — | — | EP | disclosed |
| EP-0758328-A1 | ANTI-CANCER COMPOUNDS CONTAINING CYCLOPENTAQUINAZOLINE RING | BTG INTERNATIONAL LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |
| EP-0562734-B1 | Anti-tumour compounds containing quinazoline and tetrazole rings | ZENECA LTD (GB) | 1995-12-20 | — | — | EP | disclosed |
| WO-1995030673-A1 | ANTI-CANCER COMPOUNDS CONTAINING CYCLOPENTAQUINAZOLINE RING | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1995-11-16 | — | — | WO | disclosed |
| EP-0667864-A1 | TRICYCLIC COMPOUNDS WITH PHARMACEUTICAL ACTIVITY. | ZENECA LTD (GB) | 1995-08-23 | — | — | EP | disclosed |
| WO-1994011354-A1 | TRICYCLIC COMPOUNDS WITH PHARMACEUTICAL ACTIVITY | ZENECA LIMITED (GB) | 1994-05-26 | — | — | WO | disclosed |
| EP-0562734-A1 | Anti-tumour compounds containing quinazoline and tetrazole rings | ZENECA LIMITED (GB) | 1993-09-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146539-A1 | NEW CARBOXYLIC ACID AMIDES, THE PREPARATION THEREOF AND THEIR USE AS MEDICAMENTS | OAT, ASS1, OTC | CTSL 860/4885CTSS 939/4885CTSB 997/4885 |
| US-20130237522-A1 | CARBOXYLIC ACID AMIDES, THE PREPARATION THEREOF AND THEIR USE AS MEDICAMENTS | ASS1, GOT1, OAT | CTSL 942/4885CTSS 1017/4885CTSB 865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.