Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.56 |
| ▸ | CTSS | P25774 | 4/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.55 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.54 |
| ▸ | TACR1 | P25103 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.52 |
| ▸ | ITGAV | P06756 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.50 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | TGM2 | P21980 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4280404 | 0.92 | TACR1 (0.54) | CTSLCTSSFOLH1SIRT2SIRT1 | |
| SCHEMBL7544219 | 0.90 | CTSS (0.65) | CTSLCTSSFOLH1SIRT2SIRT1 | |
| SCHEMBL10421088 | 0.89 | FOLH1 (0.62) | CTSLCTSSFOLH1SIRT2SIRT1 | |
| SCHEMBL8387978 | 0.89 | FOLH1 (0.65) | CTSLCTSSFOLH1SIRT2SIRT1 | |
| SCHEMBL7363415 | 0.86 | SIRT2 (0.59) | CTSLCTSSSIRT2SIRT1TACR1 | |
| SCHEMBL7515531 | 0.85 | FOLH1 (0.58) | CTSLCTSSFOLH1SIRT2SIRT1 | |
| SCHEMBL6841663 | 0.85 | FOLH1 (0.58) | CTSLCTSSFOLH1SIRT2SIRT1 | |
| SCHEMBL7291824 | 0.84 | CTSS (0.53) | CTSLCTSSCTSBCTSK | |
| SCHEMBL11311383 | 0.84 | CTRB1 (0.48) | CTSLCTSSTACR1CTSBCTSK | |
| SCHEMBL19520868 | 0.84 | FOLH1 (0.57) | CTSLCTSSFOLH1SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4011214-A | 3-(MORPHOLINOALKOXYIMINOMETHYL)CEPHEM COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-03-08 | — | — | US | disclosed |