Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 8/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4283222 | 0.83 | CYP26A1 (1.00) | CYP26A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4285518 | 0.78 | CYP26A1 (0.67) | CYP26A1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4284732 | 0.75 | CYP26A1 (0.64) | CYP26A1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7372118 | 0.69 | ALDH1A1 (0.50) | KDM4EALDH1A1KMT2APOLBL3MBTL1 | |
| SCHEMBL7112143 | 0.69 | ABCC9 (0.51) | KDM4EALDH1A1KMT2AL3MBTL1MEN1 | |
| SCHEMBL30704480 | 0.69 | ABCC9 (0.51) | KDM4EALDH1A1KMT2AL3MBTL1MEN1 | |
| SCHEMBL10905859 | 0.68 | KCNN4 (0.50) | CYP26A1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL808992 | 0.68 | ALDH1A1 (0.49) | CYP26A1KDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL809162 | 0.67 | L3MBTL1 (0.49) | KDM4EALDH1A1POLBL3MBTL1HPGD | |
| SCHEMBL4284739 | 0.67 | CYP26A1 (0.65) | CYP26A1MAPTCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009153566-A1 | CYP26 INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2009-12-23 | — | — | WO | disclosed |
| WO-2009153566-A1 | CYP26 INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2009-12-23 | — | — | WO | disclosed |