SCHEMBL4280607

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4284246	0.84	UBE2M (0.48)	CACNA1IKCNH2CACNA1H
	SCHEMBL4273588	0.81	CXCR3 (0.48)	CACNA1IKCNH2EPHX2CYP2D6ACKR3
	SCHEMBL14770055	0.78	KCNH2 (0.45)	CACNA1IKCNH2EPHX2SMN1; SMN2NAMPT
	SCHEMBL4271035	0.74	USP30 (0.60)	CACNA1IKCNH2ACKR3NPC1GAA
	SCHEMBL4272846	0.72	MEN1 (0.53)	CACNA1IKCNH2EPHX2CYP2D6RAB9A
	SCHEMBL4277786	0.72	MEN1 (0.47)	CACNA1IKCNH2EPHX2GAASMN1; SMN2
	SCHEMBL4277690	0.71	KCNH2 (0.48)	CACNA1IKCNH2EPHX2
	SCHEMBL4276505	0.71	P2RX7 (0.47)	CACNA1IKCNH2ACKR3
	SCHEMBL17591762	0.70	CACNA1I (0.45)	CACNA1IEPHX2NPC1GAARAB9A
	SCHEMBL4275763	0.69	SMN1; SMN2 (0.62)	NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.