Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4552154 | 1.00 | STAT3 (0.51) | STAT3ALDH1A1SMN1; SMN2KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL4293639 | 0.80 | STAT3 (0.49) | STAT3ALDH1A1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL4290177 | 0.76 | LMNA (0.45) | SMN1; SMN2KMT2ATSHR | |
| SCHEMBL4288884 | 0.74 | ADRA2A (0.52) | ALDH1A1SMN1; SMN2KMT2AMAPTHTT | |
| SCHEMBL4286339 | 0.73 | SMN1; SMN2 (0.37) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL4283648 | 0.70 | LMNA (0.43) | ALDH1A1SMN1; SMN2KMT2AHTTPOLB | |
| SCHEMBL4281778 | 0.70 | RAB9A (0.52) | ALDH1A1SMN1; SMN2KMT2AMAPTPOLB | |
| SCHEMBL4285897 | 0.70 | KMO (0.51) | ALDH1A1SMN1; SMN2KMT2APOLBMEN1 | |
| SCHEMBL14884740 | 0.69 | STAT3 (1.00) | STAT3ALDH1A1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL4292117 | 0.69 | ESR1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156612-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156612-A1 | Substituted imidazole compound and use thereof | REN, ACE, AGT | STAT3 1081/4885ALDH1A1 388/4885SMN1; SMN2 4811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.