Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 7/20 | 0.43 |
| ▸ | TACR1 | P25103 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4285494 | 0.83 | SLC6A3 (0.43) | — | |
| SCHEMBL4291883 | 0.80 | SLC6A3 (0.46) | NPSR1RIPK1KDM4ELMNACHRM3 | |
| SCHEMBL4280120 | 0.80 | LMNA (0.40) | HCRTR2NPSR1LMNA | |
| SCHEMBL4282253 | 0.79 | TACR1 (0.41) | HCRTR2TACR1NPSR1GRM5OPRL1 | |
| SCHEMBL4291624 | 0.77 | HCRTR2 (0.42) | HCRTR2NPSR1 | |
| SCHEMBL4288939 | 0.76 | TSHR (0.44) | NPSR1LMNA | |
| SCHEMBL4285849 | 0.75 | SLC6A4 (0.47) | HCRTR2 | |
| SCHEMBL4281409 | 0.74 | ALDH1A1 (0.38) | NPSR1KDM4ELMNA | |
| SCHEMBL4294072 | 0.73 | CHRNB4 (0.41) | HCRTR2 | |
| SCHEMBL4282512 | 0.73 | HCRTR2 (0.47) | HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009072643-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-11 | — | — | WO | disclosed |