SCHEMBL4282822

SCHEMBL4282822

CC(=O)Oc1cc(C)cc(Cl)c1C(=O)c1ccc(OC2CC2)cc1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.41
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
PARP10 Q53GL7 1/20 0.39
EPHX2 P34913 12/20 0.38
FAAH O00519 3/20 0.38
RAF1 P04049 2/20 0.38
MAP4K4 O95819 1/20 0.38
AR P10275 1/20 0.37
CYP2C9 P11712 1/20 0.36
CYP2J2 P51589 1/20 0.36
PGR P06401 1/20 0.36
MAPT P10636 1/20 0.36
MAPK1 P28482 1/20 0.36
HRH1 P35367 1/20 0.36
CCR3 P51677 1/20 0.36
KCNH2 Q12809 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4285539 0.84 MAP4K4 (0.45) MEN1KMT2APARP10EPHX2FAAH
SCHEMBL4285255 0.83 HPGD (0.50) MEN1KMT2ARAF1MAPTMAPK1
SCHEMBL4282990 0.82 MAPT (0.46) MEN1KMT2APARP10MAPTMAPK1
SCHEMBL4279745 0.72 PARP10 (0.39) RORCMEN1KMT2APARP10EPHX2
SCHEMBL16828682 0.72 LMNA (0.55) MEN1KMT2APARP10EPHX2FAAH
SCHEMBL4281349 0.71 KMT2A (0.57) MEN1KMT2AMAPTMAPK1
SCHEMBL4287208 0.70 BACE1 (0.49) MEN1KMT2AMAPTMAPK1
SCHEMBL4282847 0.70 KMT2A (0.46) MEN1KMT2APARP10MAPTMAPK1
SCHEMBL4283882 0.69 PARP10 (0.43) MEN1KMT2APARP10EPHX2FAAH
SCHEMBL17873483 0.69 LMNA (0.61) PARP10EPHX2MAP4K4MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-05-28 US disclosed
EP-2048150-A1 BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2009-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE SLC5A1, SLC5A2, SLC2A1 RORC 3477/4885MEN1 3776/4885KMT2A 1397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.