SCHEMBL4282979

SCHEMBL4282979

CC1CC(=O)C(C(=O)c2ccc(OC(C)C)cc2)=C(F)C1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.44
PARP10 Q53GL7 1/20 0.43
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
HPGD P15428 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
MAPT P10636 5/20 0.37
ALDH1A1 P00352 6/20 0.37
POLB P06746 2/20 0.37
TSHR P16473 1/20 0.36
TP53 P04637 2/20 0.36
THRB P10828 1/20 0.36
HTT P42858 1/20 0.36
GAA P10253 1/20 0.36
HSD17B10 Q99714 2/20 0.35
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
MCL1 Q07820 1/20 0.35
NFKB1 P19838 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4287147 0.85 LMNA (0.44) KMT2APARP10NPC1RAB9AHPGD
SCHEMBL4288581 0.82 KMT2A (0.46) KMT2APARP10NPC1RAB9AHPGD
SCHEMBL4288353 0.80 L3MBTL1 (0.44) KMT2AHPGDMAPTALDH1A1TSHR
SCHEMBL2517350 0.72 KMT2A (0.73) KMT2APARP10NPC1RAB9ASMN1; SMN2
SCHEMBL4289158 0.71 KMT2A (0.50) KMT2APARP10NPC1RAB9ASMN1; SMN2
SCHEMBL19002750 0.71 KMT2A (0.61) KMT2APARP10NPC1RAB9ASMN1; SMN2
SCHEMBL4284546 0.70 LMNA (0.45) KMT2APARP10NPC1RAB9AHPGD
SCHEMBL4279762 0.70 LMNA (0.45) KMT2APARP10NPC1RAB9AHPGD
SCHEMBL4285306 0.69 HPGD (0.50) KMT2APARP10NPC1RAB9AHPGD
SCHEMBL4283860 0.69 KMT2A (0.50) KMT2APARP10NPC1RAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-05-28 US disclosed
EP-2048150-A1 BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2009-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE SLC5A1, SLC5A2, SLC2A1 KMT2A 1397/4885PARP10 2557/4885NPC1 153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.