Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | HPN | P05981 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.45 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.45 |
| ▸ | DCUN1D1 | Q96GG9 | 5/20 | 0.44 |
| ▸ | UBE2M | P61081 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16432958 | 0.93 | DRD2 (0.46) | F10HPNPRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL17819167 | 0.93 | DRD2 (0.45) | F10HPNPRSS1PRSS2PRSS3 | |
| SCHEMBL17819176 | 0.90 | FAAH (0.44) | F10HPNPRSS1PRSS2PRSS3 | |
| Fumaric Acid SCHEMBL17819175 | 0.90 | HTR2A (0.48) | F10HPNPRSS1PRSS2PRSS3 | |
| Maleic Acid SCHEMBL17819174 | 0.90 | HTR2A (0.48) | F10HPNPRSS1PRSS2PRSS3 | |
| SCHEMBL16439292 | 0.89 | DCUN1D1 (0.47) | F10HPNPRSS1PRSS2PRSS3 | |
| SCHEMBL16433000 | 0.87 | FAAH (0.45) | DCUN1D1UBE2MDRD2DRD4DRD3 | |
| SCHEMBL424816 | 0.87 | DRD2 (0.57) | DRD2DRD4DRD3FAAHCES2 | |
| Hydrochloric Acid SCHEMBL16432898 | 0.86 | FAAH (0.45) | DRD2DRD4DRD3PRKAA2FAAH | |
| SCHEMBL425081 | 0.86 | OPRM1 (0.53) | DRD2DRD4DRD3PRKAA2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353082-B2 | Pharmaceutical compounds | BIAL—PORTELA & CA, S.A. (PT) | 2016-05-31 | — | — | US | disclosed |
| US-9353082-B2 | Pharmaceutical compounds | BIAL—PORTELA & CA, S.A. (PT) | 2016-05-31 | — | — | US | disclosed |
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2012-03-15 | — | — | US | disclosed |
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | FAAH, FAAH2, ASAH1 | F10 954/4885HPN 237/4885PRSS1 471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.