Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 9/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | BPTF | Q12830 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4296086 | 0.83 | BRD4 (0.38) | L3MBTL1ALDH1A1BRD9KDM4EMEN1 | |
| SCHEMBL4292123 | 0.82 | MAPT (0.36) | CACNA1GCACNA1HCACNA1IL3MBTL1ALDH1A1 | |
| SCHEMBL4498149 | 0.75 | RAB9A (0.55) | MAPK14MTORL3MBTL1ALDH1A1BPTF | |
| SCHEMBL26124920 | 0.74 | DGAT1 (0.45) | MAPK14CACNA1GCACNA1HCACNA1IL3MBTL1 | |
| SCHEMBL8281636 | 0.73 | ALDH1A1 (0.39) | MAPK14MTORL3MBTL1ALDH1A1BPTF | |
| SCHEMBL16651949 | 0.68 | HTT (0.42) | L3MBTL1ALDH1A1KDM4EMEN1USP2 | |
| SCHEMBL4292263 | 0.67 | NPC1 (0.50) | MTORALDH1A1BPTFKAT2BBRD9 | |
| SCHEMBL15553026 | 0.65 | BRD4 (0.41) | CACNA1GCACNA1HCACNA1IL3MBTL1ALDH1A1 | |
| SCHEMBL23318253 | 0.64 | KAT2B (0.43) | MTORALDH1A1BPTFKAT2BBRD9 | |
| SCHEMBL8281635 | 0.64 | MTOR (0.43) | MTORALDH1A1BPTFKAT2BBRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009158258-A1 | HERBICIDAL DIHYDRO OXO SIX-MEMBERED AZINYL ISOXAZOLINES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-12-30 | — | — | WO | disclosed |