Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 5/20 | 0.41 |
| ▸ | FNTB | P49356 | 5/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | GPER1 | Q99527 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4283330 | 0.84 | RBP4 (0.35) | BRD4 | |
| SCHEMBL4285459 | 0.81 | NOTUM (0.42) | — | |
| SCHEMBL4563464 | 0.78 | HDAC1 (0.33) | — | |
| SCHEMBL4284878 | 0.73 | NOTUM (0.49) | DRD2GPR119 | |
| SCHEMBL13656838 | 0.71 | GPR119 (0.41) | FNTAFNTBDRD2GPR119NR1H2 | |
| SCHEMBL4431917 | 0.70 | S1PR1 (0.53) | — | |
| SCHEMBL4427175 | 0.70 | S1PR1 (0.44) | — | |
| SCHEMBL773073 | 0.67 | DRD2 (0.64) | DRD2 | |
| SCHEMBL13656966 | 0.66 | GPR119 (0.47) | DRD2GPR119BRD4 | |
| SCHEMBL19329123 | 0.66 | DRD2 (0.48) | DRD2GPR119NR1H2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151626-A1 | SUBSTITUTED (1, 2, 4-0XADIAZ0L-3-YL) INDOLIN-1-YL CARBOXYLIC ACID DERIVATIVES USEFUL AS S1P1 AGONISTS | ARENA PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |