SCHEMBL4284583

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9304725	0.79	ALDH1A1 (0.38)	ALDH1A1ABCB11NR3C1CYP1A2CYP3A4
	SCHEMBL4285629	0.77	CYP3A4 (0.40)	ALDH1A1CYP3A4HPGDTDP1
	SCHEMBL2976682	0.72	ALDH1A1 (0.55)	ALDH1A1ABCB11NR3C1CYP1A2CYP3A4
	SCHEMBL6153417	0.71	HSP90AA1 (0.37)	ALDH1A1ABCB11NR3C1CYP1A2CYP3A4
	SCHEMBL188261	0.71	ALOX15 (0.38)	ALDH1A1ABCB11NR3C1CYP1A2CYP3A4
	SCHEMBL1022261	0.70	ALDH1A1 (0.52)	ALDH1A1ABCB11NR3C1CYP1A2CYP3A4
	SCHEMBL30507607	0.70	ALDH1A1 (0.52)	ALDH1A1ABCB11NR3C1CYP1A2CYP3A4
	SCHEMBL11718845	0.70	ALDH1A1 (0.61)	ALDH1A1ABCB11NR3C1CYP1A2CYP3A4
	SCHEMBL1093861	0.70	ABCB11 (0.32)	ALDH1A1ABCB11NR3C1CYP1A2CYP3A4
	SCHEMBL3367043	0.68	MIF (0.34)	ALDH1A1ABCB11NR3C1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.