Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | WNT1 | P04628 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.54 |
| ▸ | RORC | P51449 | 1/20 | 0.53 |
| ▸ | WNT3A | P56704 | 4/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | RET | P07949 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | FLT4 | P35916 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21286084 | 0.86 | WNT1 (0.64) | KMT2AMEN1NPC1LMNAPKM | |
| SCHEMBL4288489 | 0.78 | MAPT (0.60) | NPC1LMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL3714852 | 0.78 | KMT2A (1.00) | KMT2AMEN1NPC1LMNAPKM | |
| SCHEMBL19350228 | 0.78 | NTRK1 (0.55) | ALDH1A1HTTSMN1; SMN2L3MBTL1WNT1 | |
| SCHEMBL1948079 | 0.77 | KMT2A (0.83) | KMT2AMEN1NPC1LMNAPKM | |
| SCHEMBL29640907 | 0.75 | WNT1 (0.73) | KMT2AMEN1WNT1GSK3BDYRK1A | |
| SCHEMBL21285856 | 0.75 | WNT1 (0.73) | KMT2AMEN1WNT1GSK3BDYRK1A | |
| SCHEMBL4285505 | 0.75 | ALDH1A1 (0.64) | NPC1LMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8331684 | 0.75 | MEN1 (0.79) | KMT2AMEN1NPC1LMNAPKM | |
| SCHEMBL22953826 | 0.74 | RORC (0.57) | KMT2AMEN1NPC1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156582-A1 | Pyrazole Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156582-A1 | Pyrazole Compound | GSK3B, GSK3A, GSKIP | KMT2A 871/4885MEN1 1910/4885NPC1 1266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.