Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5652285 | 0.83 | L3MBTL1 (0.52) | L3MBTL1EPHX2TAAR1HTTMEN1 | |
| SCHEMBL4278391 | 0.76 | CYP3A4 (0.60) | L3MBTL1MEN1KMT2ATSHRTP53 | |
| SCHEMBL7539729 | 0.75 | EPHX2 (0.54) | L3MBTL1EPHX2TAAR1HTTTSHR | |
| SCHEMBL3597434 | 0.72 | HTT (0.47) | L3MBTL1EPHX2TAAR1HTTALDH1A1 | |
| SCHEMBL7380729 | 0.70 | ACE (0.49) | L3MBTL1EPHX2TAAR1HTTTSHR | |
| SCHEMBL31748828 | 0.70 | POLB (0.49) | HTTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL27861577 | 0.70 | EPHX2 (0.53) | L3MBTL1EPHX2TAAR1MEN1KMT2A | |
| SCHEMBL27536629 | 0.70 | CPN1 (0.53) | L3MBTL1SLC6A2SLC6A3 | |
| SCHEMBL16191445 | 0.70 | HTT (0.54) | L3MBTL1EPHX2TAAR1HTTALDH1A1 | |
| SCHEMBL4564333 | 0.70 | HTT (0.50) | L3MBTL1EPHX2TAAR1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | SULT2A1, STS, SULT1A1 | L3MBTL1 4883/4885EPHX2 2526/4885TAAR1 4187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.