SCHEMBL4288651

SCHEMBL4288651

COc1ccc(C(CCl)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ KIF11 P52732 11/20 0.60
▸ KCNH2 Q12809 1/20 0.60
▸ CA4 P22748 1/20 0.48
▸ LMNA P02545 1/20 0.48
▸ HTT P42858 1/20 0.48
▸ SMN1; SMN2 Q16637 1/20 0.48
▸ LTA4H P09960 2/20 0.47
▸ SIGMAR1 Q99720 1/20 0.43
▸ TRPA1 O75762 1/20 0.42
▸ CA12 O43570 1/20 0.42
▸ CA1 P00915 1/20 0.42
▸ CA2 P00918 1/20 0.42
▸ CA7 P43166 1/20 0.42
▸ CA9 Q16790 1/20 0.42
▸ CA14 Q9ULX7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9694723 1.00 KIF11 (0.60) KIF11KCNH2CA4LMNAHTT
SCHEMBL29832496 0.83 KIF11 (0.50) KIF11KCNH2CA4LMNAHTT
SCHEMBL13060384 0.82 KIF11 (0.62) KIF11KCNH2CA4LMNAHTT
SCHEMBL462675 0.82 KIF11 (0.62) KIF11KCNH2CA4LMNAHTT
SCHEMBL8208883 0.81 TSHR (0.48) KIF11
SCHEMBL8592606 0.81 KIF11 (0.60) KIF11KCNH2CA4LMNAHTT
SCHEMBL17964412 0.81 KIF11 (0.70) KIF11KCNH2CA4LMNAHTT
SCHEMBL5838167 0.81 KIF11 (0.60) KIF11KCNH2CA4LMNAHTT
SCHEMBL15212173 0.79 KIF11 (0.68) KIF11KCNH2CA4LMNAHTT
SCHEMBL22150730 0.79 KIF11 (0.71) KIF11KCNH2CA4LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12503486-B2 Compound or salt thereof and preparation method and application of same ZHEJIANG PEPTITES BIOTECH CO., LTD. (CN) 2025-12-23 — — US disclosed
US-20240116980-A1 COMPOUND OR SALT THEREOF AND PREPARATION METHOD AND APPLICATION OF SAME ZHEJIANG PEPTITES BIOTECH CO., LTD (CN) 2024-04-11 — — US disclosed
CN-115698212-A Binder and preparation method thereof, secondary battery, battery module, battery pack and electric device 宁德时代新能源科技股份有限公司 2023-02-03 — — CN disclosed
US-20210277051-A1 COMPOUND OR SALT THEREOF AND PREPARATION METHOD AND APPLICATION OF SAME ZHEJIANG PEPTITES BIOTECH CO., LTD (CN) 2021-09-09 — — US disclosed
US-20190264203-A1 GLYCOCONJUGATES OF RNA INTERFERENCE AGENTS ALNYLAM PHARMACEUTICALS INC (US) 2019-08-29 — — US disclosed
US-10131907-B2 Glycoconjugates of RNA interference agents ALNYLAM PHARMACEUTICALS, INC. (US) 2018-11-20 — — US disclosed
US-20150065558-A1 Glycoconjugates of RNA Interference Agents BANK OF AMERICA, N.A. 2015-03-05 — — US disclosed
US-8877917-B2 Glycoconjugates of RNA interference agents ALNYLAM PHARMACEUTICALS, INC. (US) 2014-11-04 — — US disclosed
US-20090203135-A1 Glycoconjugates of RNA Interference Agents ALNYLAM PHARMACEUTICALS, INC. (US) 2009-08-13 — — US disclosed
WO-2008131419-A2 GLYCOCONJUGATES OF RNA INTERFERENCE AGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2008-10-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210277051-A1 COMPOUND OR SALT THEREOF AND PREPARATION METHOD AND APPLICATION OF SAME SEM1, REN, SETDB1 KIF11 2009/4885KCNH2 3525/4885CA4 744/4885
US-20150065558-A1 Glycoconjugates of RNA Interference Agents RNASE1, B3GAT3, UGCG KIF11 2760/4885KCNH2 4807/4885CA4 3604/4885
US-10131907-B2 Glycoconjugates of RNA interference agents RNASE1, B3GAT3, UGCG KIF11 2760/4885KCNH2 4807/4885CA4 3604/4885
US-20240116980-A1 COMPOUND OR SALT THEREOF AND PREPARATION METHOD AND APPLICATION OF SAME SEM1, REN, SETDB1 KIF11 2009/4885KCNH2 3525/4885CA4 744/4885
US-20190264203-A1 GLYCOCONJUGATES OF RNA INTERFERENCE AGENTS RNASE1, B3GAT3, UGCG KIF11 2760/4885KCNH2 4807/4885CA4 3604/4885
US-12503486-B2 Compound or salt thereof and preparation method and application of same SEM1, REN, SETDB1 KIF11 2009/4885KCNH2 3525/4885CA4 744/4885
US-20090203135-A1 Glycoconjugates of RNA Interference Agents RNASE1, B3GAT3, UGCG KIF11 2760/4885KCNH2 4807/4885CA4 3604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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