SCHEMBL4290748

SCHEMBL4290748

OCCCCNCCCO

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 8/20 0.42
CA12 O43570 6/20 0.42
CA9 Q16790 6/20 0.42
CYP1A2 P05177 3/20 0.42
CA4 P22748 3/20 0.42
CA6 P23280 3/20 0.42
CA5A P35218 3/20 0.42
CA7 P43166 3/20 0.42
CA14 Q9ULX7 3/20 0.42
CA5B Q9Y2D0 3/20 0.42
TSHR P16473 2/20 0.42
F13A1 P00488 2/20 0.42
ALOX15 P16050 2/20 0.42
CYP2C19 P33261 2/20 0.42
THPO P40225 2/20 0.42
ALDH1A1 P00352 1/20 0.42
MEN1 O00255 1/20 0.42
CASP2 P42575 1/20 0.42
RECQL P46063 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9801640 0.97 CA2 (0.44) CA2CA12CA9CYP1A2CA4
SCHEMBL9801593 0.97 CA2 (0.44) CA2CA12CA9CYP1A2CA4
SCHEMBL9801337 0.97 CA2 (0.44) CA2CA12CA9CYP1A2CA4
SCHEMBL9801537 0.97 CA2 (0.44) CA2CA12CA9CYP1A2CA4
SCHEMBL2785093 0.97 CA2 (0.40) CA2CA12CA9CYP1A2CA4
SCHEMBL9801795 0.97 CA2 (0.44) CA2CA12CA9CYP1A2CA4
SCHEMBL9801792 0.97 CA2 (0.44) CA2CA12CA9CYP1A2CA4
SCHEMBL9801304 0.97 CA2 (0.44) CA2CA12CA9CYP1A2CA4
SCHEMBL9801743 0.97 CA2 (0.44) CA2CA12CA9CYP1A2CA4
SCHEMBL9801077 0.97 CA2 (0.44) CA2CA12CA9CYP1A2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4387607-A1 NANOPARTICLE COMPOSITIONS CONTAINING SUGAR FUNCTIONALIZED NUCLEIC ACID CARRIERS Tiba Biotech LLC (US) 2024-06-26 EP claimed
CN-117897152-A Nanoparticle compositions containing sugar-functionalized nucleic acid vectors 蒂巴生物技术有限公司 2024-04-16 CN claimed
US-11859201-B2 Nanoparticle compositions containing sugar functionalized nucleic acid carriers TIBA BIOTECH LLC (US) 2024-01-02 US claimed
WO-2023022926-A1 NANOPARTICLE COMPOSITIONS CONTAINING SUGAR FUNCTIONALIZED NUCLEIC ACID CARRIERS TIBA BIOTECH LLC (US) 2023-02-23 WO claimed
CN-115702005-A Vectors for efficient nucleic acid delivery 蒂巴生物技术有限公司 2023-02-14 CN claimed
EP-1463506-B1 SUBSTITUTED QUINAZOLINE DERIVATIVES AS INHIBITORS OF AURORA KINASES ASTRAZENECA AB (SE) 2009-10-21 EP claimed
US-7402585-B2 Substituted quinazoline derivatives as inhibitors of aurora kinases ASTRAZENECA AB (SE) 2008-07-22 US claimed
EP-4387607-A1 NANOPARTICLE COMPOSITIONS CONTAINING SUGAR FUNCTIONALIZED NUCLEIC ACID CARRIERS Tiba Biotech LLC (US) 2024-06-26 EP disclosed
CN-117897152-A Nanoparticle compositions containing sugar-functionalized nucleic acid vectors 蒂巴生物技术有限公司 2024-04-16 CN disclosed
US-20230219881-A1 Synthesis of Spermidine, Spermine, and Free Bases Thereof Compound Solutions Inc. (US) 2023-07-13 US disclosed
US-20230219881-A1 Synthesis of Spermidine, Spermine, and Free Bases Thereof Compound Solutions Inc. (US) 2023-07-13 US disclosed
WO-2023022926-A1 NANOPARTICLE COMPOSITIONS CONTAINING SUGAR FUNCTIONALIZED NUCLEIC ACID CARRIERS TIBA BIOTECH LLC (US) 2023-02-23 WO disclosed
CN-115702005-A Vectors for efficient nucleic acid delivery 蒂巴生物技术有限公司 2023-02-14 CN disclosed
EP-0602209-A1 OXYTOCIN ANTAGONIST OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-06-22 EP disclosed
EP-0382185-B1 Carbostyril derivatives OTSUKA PHARMA CO LTD (JP) 1994-06-15 EP disclosed
WO-1994001113-A1 OXYTOCIN ANTAGONIST OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1994-01-20 WO disclosed
US-5240630-A Refrigeration compositions containing diester-amides of dialkanolamines ETHYL CORPORATION (US) 1993-08-31 US disclosed
US-5225402-A Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-07-06 US disclosed
US-4992150-A Telomer with alpha-olefin;oil and fuel additive NIPPON OIL CO, LTD. (JP) 1991-02-12 US disclosed
EP-0382185-A2 Carbostyril derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-08-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219881-A1 Synthesis of Spermidine, Spermine, and Free Bases Thereof SRM, SMS, SMOX CA2 2235/4885CA12 3441/4885CA9 2458/4885
US-11859201-B2 Nanoparticle compositions containing sugar functionalized nucleic acid carriers TLR9, TLR3, TSG101 CA2 2266/4885CA12 818/4885CA9 828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.