Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2BTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3MPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PPARGSLC6A2SLC6A3SLC6A4SMOTYK2pol
The experimentally established mechanism targets of Maleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL14715835 | 1.00 | — | — | |
| Fumaric Acid SCHEMBL258677 | 1.00 | — | — | |
| Fumaric Acid SCHEMBL7620807 | 1.00 | TSHR (0.90) | — | |
| Maleic Acid SCHEMBL7620797 | 1.00 | TSHR (0.90) | — | |
| Fumaric Acid SCHEMBL8157540 | 0.95 | TSHR (0.82) | — | |
| Fumaric Acid SCHEMBL8157542 | 0.95 | TSHR (0.82) | — | |
| Maleic Acid SCHEMBL994743 | 0.95 | TSHR (0.82) | — | |
| Fumaric Acid SCHEMBL12488514 | 0.95 | TSHR (0.82) | — | |
| Fumaric Acid SCHEMBL994746 | 0.95 | TSHR (0.82) | — | |
| Fumaric Acid SCHEMBL12488512 | 0.95 | TSHR (0.82) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1055 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4734970-A1 | COMPOSITION COMPRISING HINOKITIOL AND ZINC SALT FOR USE IN THE TREATMENT OF HERPES LABIALIS | AAA Investments B.V. (NL) | 2026-05-06 | — | — | EP | claimed |
| US-12551425-B2 | Aqueous zinc oral care compositions with fluoride | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2026-02-17 | — | — | US | claimed |
| EP-4466075-B1 | ORAL CARE COMPOSITION | UNILEVER IP HOLDINGS B V (NL) | 2025-08-13 | — | — | EP | claimed |
| EP-4465955-B1 | ORAL CARE COMPOSITION | UNILEVER IP HOLDINGS B V (NL) | 2025-07-30 | — | — | EP | claimed |
| EP-4584337-A1 | ZINC OXIDE-FUNCTIONALIZED CALCIUM CARBONATE COMPOSITE | Omya International AG (CH) | 2025-07-16 | — | — | EP | claimed |
| CN-120158034-A | PVC/ABS alloy material and preparation method and application thereof | 金发科技股份有限公司 | 2025-06-17 | — | — | CN | claimed |
| CN-120118252-A | Preparation method of high molecular surfactant for lithium-sulfur battery | 天能电池集团股份有限公司 | 2025-06-10 | — | — | CN | claimed |
| EP-4540326-A1 | STORAGE STABILIZATION AGENT FOR STABILIZING AQUEOUS COMPOSITIONS, PROCESS FOR STABILIZING AND USES THEREOF | Omya International AG (CH) | 2025-04-23 | — | — | EP | claimed |
| CN-119855876-A | Zinc oxide functionalized calcium carbonate composite material | OMYA国际股份公司 | 2025-04-18 | — | — | CN | claimed |
| CN-119421931-A | Storage stabilizer for stabilizing aqueous compositions, method for stabilizing same and use thereof | 欧米亚国际集团 | 2025-02-11 | — | — | CN | claimed |
| US-4861816-A | Polyvinyl chloride resin composition for powder molding | SUMITOMO CHEMICAL COMPANY (JP) | 1989-08-29 | — | — | US | claimed |
| EP-0328153-A1 | A process for producing metal salts of ether carboxylic acids | NIPPON SHOKUBAI CO., LTD. (JP) | 1989-08-16 | — | — | EP | claimed |
| EP-0303509-A2 | Developer sheet | THE MEAD CORPORATION (US) | 1989-02-15 | — | — | EP | claimed |
| EP-0109102-B1 | STORAGE STABLE TOPICAL PHARMACEUTICAL COMPOSITION INCLUDING NITROGEN-CONTAINING STABILIZERS | THE PROCTER & GAMBLE COMPANY (US) | 1988-01-20 | — | — | EP | claimed |
| US-4664906-A | SYNERGISTIC MIXTURE OF HEXEDINE AND ZINC SALT | JOHNSON & JOHNSON PRODUCTS INC. (US) | 1987-05-12 | — | — | US | claimed |
| CN-85103393-A | MIXTURE FOR MOUTH | — | 1986-12-03 | — | — | CN | claimed |
| EP-0173568-A2 | Oral compositions | Johnson & Johnson Products Inc. (US) | 1986-03-05 | — | — | EP | claimed |
| EP-0109102-A2 | Storage stable topical pharmaceutical composition including nitrogen-containing stabilizers | THE PROCTER & GAMBLE COMPANY (US) | 1984-05-23 | — | — | EP | claimed |
| US-4261982-A | ZINC ERYTHROMYCIN FOR ACNE | THE PROCTER & GAMBLE COMPANY (US) | 1981-04-14 | — | — | US | claimed |
| US-3996142-A | Smoke and fire retardants for halogen-containing plastic compositions comprising the reaction product of magnesium oxide and a zinc salt of an acid | NL INDUSTRIES, INC. (US) | 1976-12-07 | — | — | US | claimed |