Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3731782 | 0.87 | ACP1 (0.55) | KDM4EHSD17B10ALDH1A1HPGDKMT2A | |
| SCHEMBL4305912 | 0.83 | ACP1 (0.50) | MPOKDM4EHSD17B10HRH3ALDH1A1 | |
| SCHEMBL17865106 | 0.81 | DRD2 (0.50) | DRD2 | |
| SCHEMBL17865162 | 0.78 | ALDH1A1 (0.50) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL19743156 | 0.78 | ALDH1A1 (0.49) | ALDH1A1 | |
| SCHEMBL27804965 | 0.75 | HTR6 (0.62) | DRD2MPOKDM4EALDH1A1KMT2A | |
| SCHEMBL1055073 | 0.73 | OPRM1 (0.61) | KDM4EALDH1A1 | |
| SCHEMBL10830932 | 0.73 | MAPK10 (0.56) | DRD2MPOHRH3KAT2BFGFR1 | |
| SCHEMBL6402270 | 0.70 | KMT2A (0.50) | DRD2KDM4EHSD17B10HRH3KMT2A | |
| SCHEMBL1054619 | 0.70 | KAT2B (0.50) | KDM4EALDH1A1SMN1; SMN2HTTKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090281100-A1 | Benzimidazole quinolinones and uses thereof | BARSANTI PAUL A | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281100-A1 | Benzimidazole quinolinones and uses thereof | GAA, ALPI, IL4I1 | DRD2 4779/4885MPO 115/4885KDM4E 2423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.