SCHEMBL4292204

SCHEMBL4292204

CCOc1ccc(C(O)c2c(O)cc(COC(C)=O)cc2Cl)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
FFAR1 O14842 4/20 0.40
SLC5A1 P13866 1/20 0.39
SLC5A2 P31639 1/20 0.39
NPBWR1 P48145 1/20 0.38
MCHR1 Q99705 1/20 0.38
ACACB O00763 3/20 0.38
ACACA Q13085 1/20 0.38
LTA4H P09960 1/20 0.38
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
POLB P06746 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
LMNA P02545 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
NPC1 O15118 1/20 0.37
MAPT P10636 1/20 0.37
MAPK1 P28482 1/20 0.37
APOBEC3A P31941 1/20 0.37
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4287172 0.88 NPBWR1 (0.41) ALDH1A1SLC5A1SLC5A2NPBWR1MCHR1
SCHEMBL4292194 0.88 MAOB (0.40) ALDH1A1FFAR1SLC5A1SLC5A2ACACB
SCHEMBL4281420 0.86 ACACB (0.37) FFAR1NPBWR1MCHR1ACACBMEN1
SCHEMBL4281303 0.79 SLC5A1 (0.40) SLC5A1SLC5A2ACACBACACALTA4H
SCHEMBL4288165 0.79 ALDH1A1 (0.48) ALDH1A1SLC5A1SLC5A2LTA4HKMT2A
SCHEMBL4293026 0.79 SMN1; SMN2 (0.45) ALDH1A1SLC5A1SLC5A2LTA4HMEN1
SCHEMBL4283898 0.77 POLB (0.47) ALDH1A1MEN1KMT2APOLBTDP1
SCHEMBL4285592 0.76 POLB (0.39) ALDH1A1FFAR1SLC5A1SLC5A2MEN1
SCHEMBL27767699 0.75 NPBWR1 (0.38) ALDH1A1NPBWR1MCHR1LMNAL3MBTL1
SCHEMBL4285479 0.74 ALDH1A1 (0.36) ALDH1A1MEN1KMT2APOLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-05-28 US disclosed
EP-2048150-A1 BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2009-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE SLC5A1, SLC5A2, SLC2A1 ALDH1A1 896/4885FFAR1 333/4885SLC5A1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.