Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016986 | 0.79 | TK1 (0.49) | G6PC1ALDH1A1TSHRCNR2AOC3 | |
| SCHEMBL8421536 | 0.79 | TK1 (0.49) | G6PC1ALDH1A1TSHRCNR2AOC3 | |
| SCHEMBL1931710 | 0.79 | MEN1 (0.54) | G6PC1TSHRTRPM8KDM4EOPRK1 | |
| SCHEMBL1931712 | 0.79 | MEN1 (0.54) | G6PC1TSHRTRPM8KDM4EOPRK1 | |
| SCHEMBL9687347 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TSHRAOC3KDM4E | |
| SCHEMBL1650495 | 0.76 | CA2 (0.47) | ALDH1A1TSHRCNR2AOC3KDM4E | |
| SCHEMBL516674 | 0.76 | BCHE (0.49) | ALDH1A1TSHRCNR2AOC3KDM4E | |
| SCHEMBL134524 | 0.75 | TSHR (0.60) | ALDH1A1TSHRCNR2AOC3KDM4E | |
| SCHEMBL7076295 | 0.75 | MEN1 (0.54) | G6PC1TSHRTRPM8KDM4EOPRK1 | |
| SCHEMBL8989760 | 0.75 | MEN1 (0.54) | G6PC1TSHRTRPM8KDM4EOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264433-A1 | Compounds, Compositions and Methods Comprising Triazine Derivatives | INSTITUTE FOR ONEWORLD HEALTH | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264433-A1 | Compounds, Compositions and Methods Comprising Triazine Derivatives | CFTR, PKD1, PKD2 | G6PC1 1554/4885ALDH1A1 2483/4885TSHR 984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.