Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | GABRE | P78334 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13092643 | 0.86 | SLC6A2 (0.37) | CYP2C19SLC6A2SLC6A4SLC6A3ARG1 | |
| SCHEMBL252560 | 0.82 | CYP2C19 (0.44) | CYP2C19 | |
| SCHEMBL1815192 | 0.82 | — | — | |
| SCHEMBL7370249 | 0.79 | KDM4E (0.36) | CYP2C19KDM4EKMT2AOPRM1SLC6A2 | |
| SCHEMBL27522485 | 0.79 | CYP2C19 (0.35) | CYP2C19KDM4EKMT2AOPRM1SLC6A2 | |
| SCHEMBL26667126 | 0.79 | CYP2C19 (0.61) | CYP2C19KDM4EKMT2AOPRM1SLC6A2 | |
| SCHEMBL855051 | 0.79 | OPRM1 (0.38) | CYP2C19KDM4EKMT2AOPRM1SLC6A2 | |
| Hydrochloric Acid SCHEMBL26667139 | 0.77 | CYP2C19 (0.59) | CYP2C19KDM4EKMT2AOPRM1SLC6A2 | |
| SCHEMBL2277073 | 0.77 | CYP2C19 (0.58) | CYP2C19TSHR | |
| SCHEMBL13898741 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |
| CN-114727993-A | Arylmethylene heterocyclic compounds as Kv1.3 potassium SHAKER channel blockers | D·E·萧尔研究有限责任公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-103619838-B | Piperidinyl monocarboxylic acids as S1P1 receptor agonists | 生物计划公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-102498099-B | HSL inhibitors useful in the treatment of diabetes | HOFFMAN-LA ROCHE LTD. (CH) | 2014-10-29 | — | — | CN | disclosed |
| CN-103619838-A | Novel piperidinyl monocarboxylic acids as s1p1 receptor agonists | BIOPROJET SOC CIV | 2014-03-05 | — | — | CN | disclosed |
| CN-102498099-A | HSL inhibitors useful in the treatment of diabetes | HOFFMANN LA ROCHE | 2012-06-13 | — | — | CN | disclosed |
| US-20090264466-A1 | Certain Chemical Entities, Compositions and Methods | CYTOKINETICS, INC. | 2009-10-22 | — | — | US | disclosed |
| CN-1163616-A | DC107 derivatives | KYOWA HAKKO KOGYO KK (JP) | 1997-10-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264466-A1 | Certain Chemical Entities, Compositions and Methods | MYLK, MYH2, MYH10 | CYP2C19 2274/4885KDM4E 3559/4885KMT2A 2709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.