Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.30 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL29516278 | 0.92 | OPRM1 (0.34) | OPRM1KDM4EKMT2ACYP2C19 | |
| SCHEMBL31693661 | 0.88 | CYP1A2 (0.37) | OPRM1KDM4EKMT2ACYP2C19CYP2D6 | |
| SCHEMBL29951019 | 0.87 | SLC6A2 (0.39) | OPRM1CYP2C19SLC6A2SLC6A4SLC6A3 | |
| Chlorobenzene SCHEMBL28751598 | 0.83 | OPRM1 (0.44) | OPRM1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL30716833 | 0.83 | CYP2C19 (0.42) | CYP2C19FFAR3SLC6A3 | |
| SCHEMBL245571 | 0.83 | — | — | |
| SCHEMBL1292699 | 0.83 | CYP2D6 (0.41) | OPRM1KDM4EKMT2ACYP2C19SLC6A2 | |
| Hydrochloric Acid SCHEMBL11173735 | 0.80 | — | — | |
| SCHEMBL29090668 | 0.80 | KDM4E (0.48) | OPRM1KDM4EKMT2ASMYD3 | |
| SCHEMBL4294182 | 0.79 | CYP2C19 (0.37) | OPRM1KDM4EKMT2ACYP2C19SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 302 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | claimed |
| EP-3215489-B1 | METHOD FOR THE PREPARATION OF 1-(2-HALOGEN-ETHYL)-4 PIPERIDINE-CARBOXYLIC ACID ETHYL ESTERS | OLON SPA (IT) | 2019-07-24 | — | — | EP | claimed |
| US-10023535-B2 | Method for the preparation of 1-(2-halogen-ethyl)-4 piperidine-carboxylic acid ethyl esters | OLON S.P.A. (IT) | 2018-07-17 | — | — | US | claimed |
| US-20170313657-A1 | METHOD FOR THE PREPARATION OF 1-(2-HALOGEN-ETHYL)-4 PIPERIDINE-CARBOXYLIC ACID ETHYL ESTERS | OLON S.P.A. (IT) | 2017-11-02 | — | — | US | claimed |
| EP-3215489-A1 | METHOD FOR THE PREPARATION OF 1-(2-HALOGEN-ETHYL)-4 PIPERIDINE-CARBOXYLIC ACID ETHYL ESTERS | OLON S.p.A. (IT) | 2017-09-13 | — | — | EP | claimed |
| WO-2016071792-A1 | METHOD FOR THE PREPARATION OF 1-(2-HALOGEN-ETHYL)-4 PIPERIDINE-CARBOXYLIC ACID ETHYL ESTERS | LABORATORIO CHIMICO INTERNAZIONALE S.P.A. (IT) | 2016-05-12 | — | — | WO | claimed |
| EP-0387057-B1 | Surface-treating agents for copper and copper alloy | TOKAI ELECTRO CHEMICAL CO (JP) | 1993-10-20 | — | — | EP | claimed |
| US-12478621-B2 | Substituted aminoquinolones as dgkalpha inhibitors for immune activation | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2025-11-25 | — | — | US | disclosed |
| CN-119564686-A | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-119523983-A | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119424429-A | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-115003665-B | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2024-11-08 | — | — | CN | disclosed |
| US-20240299627-A1 | Inverse thermogelling polyoxazoline copolymers | JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG (DE) | 2024-09-12 | — | — | US | disclosed |
| EP-0300462-B1 | HETEROCYCLIC PEROXYCARBOXYLIC ACIDS | AUSIMONT S.p.A. (IT) | 1993-09-29 | — | — | EP | disclosed |
| EP-0292735-B1 | PROCESS FOR PREPARING ALPHA-(ALKYLPHENYL)-4-(HYDROXYDIPHENYLMETHYL)-1-PIPERIDINE BUTANOL | ERREGIERRE INDUSTRIA CHIMICA Spa (IT) | 1992-08-19 | — | — | EP | disclosed |
| US-5112978-A | Preparation of terfenadine | ERREGIERRE INDUSTRIA CHIMICA S.P.A. (IT) | 1992-05-12 | — | — | US | disclosed |
| US-5071584-A | Storage stable, heat resistant | AUSIMONT S.P.A. (IT) | 1991-12-10 | — | — | US | disclosed |
| US-4950674-A | Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1990-08-21 | — | — | US | disclosed |
| EP-0300462-A2 | Heterocyclic peroxycarboxylic acids | AUSIMONT S.p.A. (IT) | 1989-01-25 | — | — | EP | disclosed |
| EP-0068669-A1 | Secondary phenylethanol amines, processes for their preparation and their pharmaceutical application | BEECHAM GROUP PLC (GB) | 1983-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10023535-B2 | Method for the preparation of 1-(2-halogen-ethyl)-4 piperidine-carboxylic acid ethyl esters | UMPS, UCK2, EFTUD2 | OPRM1 932/4885KDM4E 152/4885KMT2A 2887/4885 |
| US-12478621-B2 | Substituted aminoquinolones as dgkalpha inhibitors for immune activation | DGKK, DGKG, DGKA | OPRM1 4717/4885KDM4E 1315/4885KMT2A 2132/4885 |
| US-20170313657-A1 | METHOD FOR THE PREPARATION OF 1-(2-HALOGEN-ETHYL)-4 PIPERIDINE-CARBOXYLIC ACID ETHYL ESTERS | UMPS, UCK2, EFTUD2 | OPRM1 932/4885KDM4E 152/4885KMT2A 2887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.