SCHEMBL4296451

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4296856	0.96	MAOA (0.57)	MAOACASP3MAPTMAPK1TDP1
	SCHEMBL4293698	0.90	MEN1 (0.62)	MAOACASP3MAPTMAPK1TDP1
	SCHEMBL12960466	0.90	MAOA (0.69)	MAOACASP3MAPTMAPK1TDP1
	SCHEMBL4304874	0.90	MAOA (0.62)	MAOACASP3MAPTMAPK1TDP1
	SCHEMBL29074195	0.89	MAOA (0.64)	MAOACASP3MAPTMAPK1TDP1
	SCHEMBL10876455	0.86	MAOA (0.57)	MAOACASP3MAPTMAPK1TDP1
	SCHEMBL4622432	0.86	CASP3 (0.69)	MAOACASP3MAPTMAPK1TDP1
	SCHEMBL11425486	0.85	MAOA (0.61)	MAOACASP3MAPTMAPK1TDP1
	SCHEMBL11420190	0.84	CASP3 (0.59)	MAOACASP3MAPTTDP1L3MBTL1
	SCHEMBL29358319	0.84	CASP3 (0.71)	MAOACASP3MAPK1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.