Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.51 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | MC5R | P33032 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4300137 | 0.85 | TRPV1 (0.60) | EPHX2TRPV1DGAT1HDAC1HDAC6 | |
| SCHEMBL4409346 | 0.75 | TRPV1 (0.46) | EPHX2TRPV1DGAT1HDAC1HDAC6 | |
| SCHEMBL13611460 | 0.72 | DGAT1 (0.62) | EPHX2TRPV1DGAT1CYP2C9CYP2C19 | |
| SCHEMBL4553345 | 0.71 | DGAT1 (0.58) | EPHX2TRPV1DGAT1CYP2C9CYP2C19 | |
| SCHEMBL13611480 | 0.70 | DGAT1 (0.65) | EPHX2DGAT1HDAC1CYP2C9CYP2C19 | |
| SCHEMBL5947865 | 0.69 | EPHX2 (1.00) | EPHX2TRPV1DGAT1CYP2C9CYP2C19 | |
| SCHEMBL4296706 | 0.69 | DGAT1 (0.62) | EPHX2TRPV1DGAT1HDAC1CYP2C9 | |
| SCHEMBL4251142 | 0.69 | EPHX2 (0.67) | EPHX2TRPV1DGAT1CYP2C9CYP2C19 | |
| SCHEMBL4291779 | 0.68 | DGAT1 (0.67) | EPHX2TRPV1DGAT1HDAC1CYP2C9 | |
| SCHEMBL4302935 | 0.68 | DGAT1 (0.62) | EPHX2TRPV1DGAT1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286791-A1 | Amide Compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286791-A1 | Amide Compounds | DLAT, DGAT2, DGAT1 | EPHX2 1912/4885TRPV1 3993/4885DGAT1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.