Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 5/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4300137 | 0.87 | TRPV1 (0.60) | TRPV1HTR2CDGAT1EPHX2HDAC1 | |
| SCHEMBL4407981 | 0.80 | DGAT1 (0.47) | HTR2CDGAT1EPHX2HDAC1HDAC2 | |
| SCHEMBL4406451 | 0.79 | DGAT1 (0.52) | DGAT1EPHX2HDAC1HDAC2SCN9A | |
| SCHEMBL4407117 | 0.77 | DGAT1 (0.49) | DGAT1EPHX2SCN9A | |
| SCHEMBL4296664 | 0.75 | EPHX2 (0.52) | TRPV1HTR2CDGAT1EPHX2HDAC1 | |
| SCHEMBL4401623 | 0.70 | DGAT1 (0.57) | DGAT1EPHX2HDAC1SCN9A | |
| SCHEMBL4553345 | 0.70 | DGAT1 (0.58) | TRPV1DGAT1EPHX2SCN9A | |
| SCHEMBL6204945 | 0.70 | CFTR (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7960871 | 0.69 | HDAC1 (0.60) | SSTR3HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL13611460 | 0.69 | DGAT1 (0.62) | TRPV1DGAT1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044055-A2 | AMIDE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008011131-A2 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-24 | — | — | WO | disclosed |